Hypothyroidism and pregnancy: new recommendations on the features of the diagnosis and treatment modality

Main Article Content

O.V. Kaminskyi
T.F. Tatarchuk


The pathology of the thyroid gland is quite common, especially in iodine deficiency regions, which include Ukraine. The probability of finding violations of the functional state of the thyroid gland in pregnant women is high, which increases the risks that burden pregnancy or make it impossible. The American Thyroid Association published new approaches to the management of pregnant women in 2017. Diagnostic and therapeutic approaches to such women are specified in them. It is noted that the normal range of thyroid-stimulating hormone (TSH) concentration in them differs from those in non-pregnant individuals and depends on the trimester of pregnancy. The detection of TSH level of more than 2.5–3.0 mIU/L is critical, indicates that women have hypothyroidism, which requires immediate replacement hormone therapy with L-thyroxine. Each pregnant woman should supplement her diet with additional intake of potassium iodide preparations at a dose of 150–200 μg daily throughout pregnancy and infant feeding.

Article Details

How to Cite
Kaminskyi, O., and T. Tatarchuk. “Hypothyroidism and Pregnancy: New Recommendations on the Features of the Diagnosis and Treatment Modality”. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine), vol. 13, no. 2, May 2017, pp. 152-7, doi:10.22141/2224-0721.13.2.2017.100605.
Clinical Thyroidology


Alexander EK, Pearce EN, Brent GA, Brown RS, et al. 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum. Thyroid. March 2017, 27(3): 315-389. doi:10.1089/thy.2016.0457.

Bernal J. Thyroid Hormones in Brain Development and Function. [Updated 2015 Sep 2]. In: De Groot LJ, Chrousos G, Dungan K, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000. Available from: https://www.ncbi.nlm.nih.gov/books/NBK285549/

WHO/ICCIDD/UNICEF. Indicators for Assessing Iodine Deficiency Disorders and Their Control Through Salt Iodization. Geneva, Switzerland: World Health Organization; 1994.

Assessment of the Iodine Deficiency Disorders and monitoring their elimination: a guide for programme managers, 3rd ed. Geneva: WHO; 2007. 98p.