Risk factors of vitamin D deficiency among Ukrainian women in Carpathian region

Main Article Content

I.V. Pankiv


Background. Vitamin D deficiency is present in over half of population worldwide.It has been long known that vitamin D deficiency contributes to the development of osteopenia and osteoporosis. As the vitamin D receptors are present in all human cells, several studies have focused on the extra-skeletal effects of vitamin D and the way it affects general health of patients. The purpose of the study was to assess some risk factors of vitamin D deficiency among Ukrainian women in Carpathian region. Materials and methods. Four hundred and ninety-five women aged 18–82 years were included in this cross-sectional study from 2014 to 2016. Serum 25-hydroxyvitamin D levels were measured in all participants after collecting their demographic and anthropometric data and past medical histories. Results. The prevalence of vitamin D deficiency and insufficiency was 91.1 %. Analysis of logistic regression shows that age (odds ratio (OR): 0.98, confidence interval (CI): 0.95–0.98) and menopause (OR: 0.49, CI: 0.25–0.98) were independent predictive factors for vitamin D deficiency. Conclusions. This study showed a high prevalence of vitamin D deficiency among Ukrainian women, especially in reproductive age.

Article Details

How to Cite
Pankiv, I. “Risk Factors of Vitamin D Deficiency Among Ukrainian Women in Carpathian Region”. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine), vol. 14, no. 1, Mar. 2018, pp. 31-34, doi:10.22141/2224-0721.14.1.2018.127088.
Original Researches


Hossein-Nezhad A, Holick MF. Vitamin D for health: a global perspective. Mayo Clin Proc. 2013 Jul;88(7):720-55. doi: 10.1016/j.mayocp.2013.05.011.

Pludowski P, Holick MF, Pilz S, et al. Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality – a review of recent evidence. Autoimmun Rev. 2013 Aug;12(10):976-89. doi: 10.1016/j.autrev.2013.02.004.

Snezhitskiy VA, Yankovskaya LV, Povoroznyuk VV, et al. Vitamin D deficiency / insufficiency among residents of the Western Region of Belarus suffering from cardiovascular pathology. Standardy medyczne. Pediatria. 2012;5(9):577-583.

Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011 Jul;96(7):1911-30. doi: 10.1210/jc.2011-0385.

Hilger J, Friedel A, Herr R, et al. A systematic review of vitamin D status in populations worldwide. Br J Nutr. 2014 Jan 14;111(1):23-45. doi: 10.1017/S0007114513001840.

Schöttker B, Jorde R, Peasey A, еt al. Vitamin D and mortality: meta-analysis of individual participant data from a large consortium of cohort studies from Europe and the United States. BMJ. 2014 Jun 17;348:g3656. doi: 10.1136/bmj.g3656.

Carlson CR, Uriu-Adams JY, Chambers CD, et al. Vitamin D Deficiency in Pregnant Ukrainian Women: Effects of Alcohol Consumption on Vitamin D Status. J Am Coll Nutr. 2017 Jan;36(1):44-56. doi: 10.1080/07315724.2016.1174091.

Ringe JD, Kipshoven C. Vitamin D-insufficiency: An estimate of the situation in Germany. Dermatoendocrinol. 2012;4(1):72–80. doi: 10.4161/derm.19829.

Pludowski P, Grant WB, Bhattoa HP, et al. Vitamin D Status in Central Europe. Int J Endocrinol. 2014;2014:589587. doi: 10.1155/2014/589587.

Holick MF. Vitamin D deficiency. N Engl J Med. 2007;357(3):266-81. doi: 10.1056/NEJMra070553.

Fuleihan GEH. Vitamin D Deficiency in the Middle East and its health consequences for children and adults. Clin Rev Bone Miner Metab. 2009;7(1):77-93. doi: 10.1007/s12018-009-9027-9.

Arabi A, El Rassi R, El-Hajj Fuleihan G. Hypovitaminosis D in developing countries-prevalence, risk factors and outcomes. Nat Rev Endocrinol. 2010;6(10):550-61. doi: 10.1038/nrendo.2010.146.

Niculescu DA, Capatina CAM, Dusceac R, Caragheorgheopol A, Poiana C. Seasonal variation of serum vitamin D levels in Romania. Arch Osteoporos. 2017 Dec 11;12(1):113. doi: 10.1007/s11657-017-0407-3.

Chirita-Emandi A, Socolov D, Haivas C, Calapiș A, Gheorghiu C, Puiu M. Vitamin D status: a different story in the very young versus the very old Romanian patients. PLoS One. 2015 May 29;10(5):e0128010. doi: 10.1371/journal.pone.0128010.

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