Male factor of sterility: algorithm of laboratory diagnosis of the causes

Main Article Content

O.V. Rykova

Abstract

Timely diagnosis of the causes of infertility is the key to the effectiveness of treatment. Given that half of the causes of this condition accounts for male factor, it is important to conduct a comprehensive study to identify the etiology and appropriate treatment, including in vitro fertilization method selection. The article describes the algorithms of laboratory diagnostic methods. Particular emphasis is placed on the rules for referring men to this survey, taking into account factors that might influence the results, optimal sets of laboratory tests and algorithms for interpreting the results. Recommendations are based on the guidelines published in 2018 — “Testosterone Therapy in Men with Hypogonadism: An Endocrine Society. Clinical Practice Guideline”.

Article Details

How to Cite
Rykova, O. “Male Factor of Sterility: Algorithm of Laboratory Diagnosis of the Causes”. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine), vol. 15, no. 1, Apr. 2019, pp. 44-49, doi:10.22141/2224-0721.15.1.2019.158693.
Section
To practicing Endocrinologists

References

Bhasin S, Brito JP, Cunningham GR, et al. Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2018 May 1;103(5):1715-1744. doi: 10.1210/jc.2018-00229.

Dohle GR, Arver S, Bettocchi C, Jones TH, Kliesch S, Punab M. Male Hypogonadism: 2015 Guideline From The European Association Of Urology. Available from: https://uroweb.org/guideline/male-hypogonadism/.

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Morales A, Bebb RA, Manjoo P, et al. Diagnosis and management of testosterone deficiency syndrome in men: clinical practice guideline. CMAJ. 2015 Dec 8;187(18):1369-77. doi: 10.1503/cmaj.150033.

Travison TG, Vesper HW, Orwoll E, et al. Harmonized reference ranges for circulating testosterone levels in men of four cohort studies in the United States and Europe. J Clin Endocrinol Metab. 2017 Apr 1;102(4):1161-1173. doi: 10.1210/jc.2016-2935.

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