Clinical course and effective treatment of varicose vein of lower limb in diabetic patients

Article Sidebar

PDF (Русский)
DOI: https://doi.org/10.22141/2224-0721.13.1.2017.96752
Keywords:
diabetes mellitus, varicose, veins, treatment

Main Article Content

Yu.O. Syniachenko
Donetsk National Medical University, Lyman, Ukraine
G.Ie. Samoilenko
Donetsk National Medical University, Lyman, Ukraine
O.V. Syniachenko
Donetsk National Medical University, Lyman, Ukraine

Abstract

Background. Type 2 diabetes mellitus (DM2) is a risk factor for arteriosclerosis of the lower extremities, and the relationship with the state of the feet venous vascular territory remains insufficiently studied, the effectiveness of surgical treatment of patients with varicose veins is not defined. Objective: to analyze the clinical course of foot varicose veins and the effectiveness of medical measures on the background of DM2. Materials and methods. The study included 302 patients (227 men and 75 women aged 29–72 years old), 16 % of which had previous phlebothrombosis and the prevalece of II, III, IV, V and VI class of venous insufficiency was 10, 14, 37 16 and 23 %, respectively. 263 patients underwent endovenous laser coagulation, and 39 — the traditional phlebectomy and ligation of perforating veins. Results. Among the examined patients with varicose veins of lower extremities DM2 was diagnosed in 9 % of cases, more often in males and elderly patients on the background of atherosclerosis of the foot vessels (iliac, femoral, tibial, popliteal artery), which was accompanied by more frequent involvement of the great saphenous vein in the process and its gate extension, the prevalence of severe grades of venous insufficiency, significantly worse the results of surgical treatment of varicose veins and greater frequency of complications, despite more frequent using of rivaroxaban and low molecular weight heparins, and the effectiveness of endovenous laser ablation after four weeks of its implementation is inferior to that in the group without DM2, while glycemic index inversely correlated with the surface tension of the venous blood, which has prognostic significance in the context of future medical interventions. Conclusions. The presence of DM2 is a risk factor for more severe feet varicose veins, is a negative predictive factor in the effectiveness of surgical treatment of the disease and the complications number.

Article Details

How to Cite
Syniachenko, Y., G. Samoilenko, and O. Syniachenko. “Clinical Course and Effective Treatment of Varicose Vein of Lower Limb in Diabetic Patients”. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine), vol. 13, no. 1, Feb. 2017, pp. 27-32, doi:10.22141/2224-0721.13.1.2017.96752.
Issue
Vol. 13 No. 1 (2017)
Section
Original Researches
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Our edition uses the copyright terms of Creative Commons for open access journals.

Authors, who are published in this journal, agree with the following terms:

  1. The authors retain rights for authorship of their article and grant to the edition the right of first publication of the article on a Creative Commons Attribution 4.0 International License, which allows others to freely distribute the published article, with the obligatory reference to the authors of original works and original publication in this journal.
  2. Directing  the article for the publication to the editorial board (publisher), the author agrees with transmitting of rights for the protection and using the article, including parts of the article, which are protected by the copyrights, such as the author’s photo, pictures, charts, tables, etc., including the reproduction in the media and the Internet; for distributing; for the translation of the manuscript in all languages; for export and import of the publications copies of the writers’ article to spread, bringing to the general information.
  3. The rights mentioned above authors transfer to the edition (publisher) for the unlimited period of validity and on the territory of all countries of the world.
  4. The authors guarantee that they have exclusive rights for using of the article, which they have sent to the edition (publisher). The edition (the publisher) is not responsible for the violation of given guarantees by the authors to the third parties.
  5. The authors have the right to conclude separate supplement agreements that relate to non-exclusive distribution of their article in the form in which it had been published in the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.
  6. The policy of the journal permits and encourages the publication of the article in the Internet (in institutional repository or on a personal website) by the authors, because it contributes to productive scientific discussion and a positive effect on efficiency and dynamics of the citation of the article.

References

Amann-Vesti B, Meier T. New therapies for varicose veins. Praxis. 2016;105(14):801-10. doi: 10.1024/1661-8157/a002401.

Balasubramanya B, Nisha C, Ramesh N, Joseph B. Staff working in ancillary departments at a tertiary care hospital in Bengaluru, Karnataka, India: How healthy are they? Indian J Occup Environ Med. 2016;20(1):44-7. doi: 10.4103/0019-5278.183844.

De Almeida Medeiros AB, de Queiroz Frazão CM, de Sá Tinôco JD, Nunes de Paiva M, Oliveira Lopes MV, Brandão de Carvalho Lira AL. Venous ulcer: risk factors and the nursing outcomes classification. Invest Educ Enferm. 2014;32(2):252-9. doi: 10.1590/S0120-53072014000200008.

Desman E, Bartow W, Anderson LH. Human skin allograft for patients with diabetic foot ulcers, venous leg ulcers, or surgical/traumatic wounds retrospective, descriptive study. Ostomy Wound Manage. 2015;61(7):16-22.

Greenhalgh DG. Management of the skin and soft tissue in the geriatric surgical patient. Surg Clin North Am 2015;95(1):103-14. doi: 10.1016/j.suc.2014.09.008.

Greer N, Foman NA, MacDonald R, Dorrian J, Fitzgerald P, Rutks I. Advanced wound care therapies for nonhealing diabetic, venous, and arterial ulcers: a systematic review. Ann Intern Med. 2013;159(8):532-42. doi: 10.7326/0003-4819-159-8-201310150-00006.

Kaspar S. Veins and diabetes. Vnitr Lek 2016;56(4):329-32.

Koppensteiner R. Hemorheology and angiology. Fortschr Med. 2012;110(7):108-10.

Matic P, Jolic S, Tanaskovic S, Soldatovic I, Katsiki N, Isenovic E, Radak D. Chronic venous disease and comorbidities. Angiology. 2015;66(6):539-44. doi: 10.1177/0003319714541988.

McInnes RL, Cullen BM, Hill KE, Price PE, Harding KG, Thomas DW, Stephens P. Contrasting host immuno-inflammatory responses to bacterial challenge within venous and diabetic ulcers. Wound Repair Regen. 2014;22(1):58-69. doi: 10.1111/wrr.12133.

Meissner MH. What is effective care for varicose veins? Phlebology. 2016;31(1):80-7. doi: 10.1177/0268355516632999.

Osmanov RR. A middle-term results of endovenous laser ablation for varicose disease of the lower extremities. Klin Khir. 2016;23(2):48-51.

Palamarchuk VI, Odnorog SI, Gvozdyak MM, Vilgash AM. Comparison of intraoperative scleroobliteration and echoscleroobliteration efficiency of varicose diseases of the lower extremities C6 class in patients by type II diabetes mellitus. Klin Khir. 2015;22(6):44-5.

Pavlović M.D. Drug treatment of chronic venous diesease. Wien Med Wochenschr. 2016;166(9-10):312-319. doi: 10.1007/s10354-016-0480-z.

Rabe E, Berboth G, Pannier F. Epidemiology of chronic venous diseases. Wien Med Wochenschr. 2016;166(9-10):260-3. doi: 10.1007/s10354-016-0465-y.

Schuller-Petrovic S. Endovenous ablation of saphenous vein varicosis. Wien Med Wochenschr. 2016;166(9-10):297-301. doi: 10.1007/s10354-016-0464-z.

Sevim Y, Unal Z, Koksoy C. Effects of surgery on microvascular function in venous insufficiency. Ann Vasc Surg. 2014;28(8):1869-77. doi: 10.1016/j.avsg.2014.07.012.

Słoczynska K, Kozka M, Marona H. Rheological properties of young and aged erythrocytes in chronic venous disease patients with varicose veins. Clin Hemorheol Microcirc. 2013;17(4):145-52. doi: 10.3233/CH-131715.

Stiegler H. Vascular ultrasonography. Internist. 2012;53(3):298-308. doi: 10.1007/s00108-011-2956-7.

Tezuka M, Kanaoka Y, Ohki T. Endovenous laser treatment for varicose veins. Nihon Geka Gakkai Zasshi. 2015;116(3):155-60.

Uthoff H, Spinedi L, Lattmann T, Broz P, Staub D. Well-Tried and New Ones — update varicose vein treatment 2016. Praxis. 2016;105(14):813-9. doi: 10.1024/1661-8157/a002405.

Warriner RA, Wilcox JR, Carter MJ, Stewart DG. More frequent visits to wound care clinics result in faster times to close diabetic foot and venous leg ulcers. Adv Skin Wound Care. 2012;25(11):494-501. doi: 10.1097/01.ASW.0000422629.03053.06.

Most read articles by the same author(s)