Peculiarities of changes in body fluid sectors in obesity found by studying its structure

Main Article Content

N.A. Kravchun
K.V. Misiura


Background. Timely diagnosis of excess body weight and obesity, by studying the body mass index and body structure parameters, including the characteristics of changes in its fluid sectors, is critical due to the significant spread of obesity and complications it may cause. Objective was to study the distribution of the body fluid sectors and the relationship with the indicators of the body composition among people with excess body weight and obesity on the example of the adult population in Kharkiv. Materials and methods. A total of 485 of Kharkiv residents were studied, all over 18 years of age. Using the method of bioimpedance analysis and according to the body mass index and gender, there was evaluated the total amount of water (L) and total, extracellular, intracellular, interstitial fluids (L). Results. It has been established that in patients with overweight of different degrees, there is an increase in the absolute amount of total water, as well as total, extracellular, interstitial and intracellular fluids. However, the relative content of these parameters decreases. The revealed changes are being intensified with the progression of the degree of obesity. Understanding of these mechanisms is important for the development of personalized approaches to
assist the population with overweight. Conclusions. For use in the clinical practice, mathematical formulas are being offered for determining the parameters of body fluid sectors in the urban population of Ukraine, without the use of instrumental methods.

Article Details

How to Cite
Kravchun, N., and K. Misiura. “Peculiarities of Changes in Body Fluid Sectors in Obesity Found by Studying Its Structure”. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine), vol. 13, no. 1, Feb. 2017, pp. 72-78, doi:10.22141/2224-0721.13.1.2017.96761.
Original Researches


WHO, 2015. Available from:

Lorenzo A, Andreoli A, Matthie J. Predicting body cell mass with bioimpedance by using theoretical methods: a technological review. Am Physiol Soc. 1997:1542-1547.

Martirosov EG, Nikolayev DV, Rudnev SG. Tekhnologii i metody opredeleniia sostava tela cheloveka [Technologies and methods for determining the composition of the human body]. Мoskow: Nauka, 2006:256 p. (in Russian).

Zaychyk AS, Churilov LP. Patokhimiia (endokrinno-metabolicheskie narusheniia) [Pathochemistry (endocrine-metabolic disorders)]. SPt: Elbi-SPt, 2007:768 p. (in Russian).

Recommendations ААСЕ/АСЕ-2016 about treatment of patients with obesity. Available from:

Ivanov GG, Kotliarova LV, Gribanov AN, Dvornikov VE. Assessment of the water sectors of the body by bioimpedance spectroscopy and dependence on sex, age and anthropometric data. In: The eighth scientific-practical conference. Main clinical hospital MIA Russia. 2006; Moskow, Russian Federation. Moskow; 2006:95-106 (in Russian).

Composition of plasma and intercellular fluid. Components of intracellular fluid. Available from:

Trushkina IV, Foloppov GP, Leontieva IV. Evaluation of body structure in patients with varying degrees of overweight. Sibirskii meditsinskii zhurnal. 2010;25(3):38-44 (in Russian).

Watson PE, Watson ID, Batt RD. Total body water volumes for adult males and females estimated from simple anthropometric measurements. Am J Clin Nutr. 1980;33(1):27-39.

Hume R, Weyers E. Relationship between total body water and surface area in normal and obese subjects. J Clin Pathol. 1971;24:234-238.

Most read articles by the same author(s)

1 2 > >>