Clinico-laboratory and instrumental features of hypertonic disease in conjunction with obliterative atherosclerosis of the lower extremities in out-patient practice
DOI:
https://doi.org/10.22141/2306-2436.8.1.2019.172616Keywords:
hypertonic disease, obliterative atherosclerosis of the lower extremities, comorbidity, intima-media thickness, lipidograma, intracardiac haemodynamicsAbstract
Background. The article is devoted to the features of obliterative atherosclerosis of the lower extremities (OALE), as well as the high-quality management of patients with hypertension and OALE comorbidity, especially after undergoing reconstructive operations on occlusion of the arteries of the lower extremities, which is an important part of the activity of primary care physicians. The purpose of the study was to evaluate the risk factors, the indicators of daily monitoring and the profile of blood pressure, intracardiac hemodynamics (according to the echocardiogram), the thickness of the intima-media complex (according to sonography of the carotid arteries) and lipidograms of patients with hypertension in combination with OALE. Results. It was found that the presence of hypertensive patients with concomitant obliterative atherosclerosis of the lower extremities complicated the clinical course of the disease (the higher average daily SAP level was 4.17%, DAP - 2.97%, and heart rate - 11.54%, p<0,05), was accompanied by a more significant violation of intracardiac haemodynamics: with an increase in echocardiographic parameters of the end-diastolic and end-systolic volumes, the end-diastolic and ultimate systolic dimensions, respectively, at 8.25%, 5.58%, 4.54%, 6.80%, thickening of the rear wall of the left ventricle at 16,18% and the interventricular membrane at 9.76% compared with those with isolated hypertension (p<0,05), the progression of atherosclerosis: in violation of lipidograma (elevated cholesterol by 11.32% and triglycerides per 29.17%, decrease in LPHD by 21.43%) and an increase in the thickness of the intima-media complex in sonographic examination of carotid arteries by 29.09% (p<0.001). Conclusions. The presence in hypertensive patients with concomitant obliterative atherosclerosis of the lower extremities complicated the clinical course of the disease.
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