Analysis of the gestational period and perinatal outcomes in women after surgical treatment of the cervix
DOI:
https://doi.org/10.22141/2306-2436.10.4.2021.246353Keywords:
complications of gestation and postpartum periods, surgical organ-preserving treatment of the cervixAbstract
Background. The purpose was to conduct a comparative analysis of the course of pregnancy and perinatal outcomes in women who underwent treatment of the cervix using various organ preserving surgical methods. Material and methods. We examined 250 women of reproductive age who underwent excision or ablative treatment of the cervix before pregnancy. The subjects were divided into five groups depending on the cervix treatment method. The study used general clinical examination protocols outlined in the regulations № 417 and № 676 issued by the Ministry of Health of Ukraine. The results. The most frequent complications of pregnancy in the patients with cervical surgery were: threatened abortion, threatened of preterm birth, anemia, low placentation, placental dysfunction, and low levels of amniotic fluid. Childbirth complications in women who underwent excision or ablation treatment of the cervix before pregnancy predominantly consisted of labor abnormalities, premature amniotic sac rupture, fetal distress, tears of the cervix and perineum. Among the complications of the postpartum period, there were isolated cases of subinvolution of the uterus, lochiometers, metroendometritis, and lactostasis. There were no cases of intrapartum and early neonatal mortality among the newborns. Conclusions. Given the high frequency of gestational and postpartum complications in women after organ-sparing surgical treatment of the cervix, it is necessary to choose the least harmful approach. The lowest incidence of complications during pregnancy, intra and postnatal periods was observed in the women who underwent laser vaporization and radio-wave ablation.
References
Вороненко Ю.В., Шекера О.Г., Горбунова О.В. Актуальні питання гінекології у практиці сімейного лікаря: навч. посіб. для лікарів-інтернів і лікарів-слухачів закл. (ф-тів) післядиплом. освіти / за ред. : Ю. В. Вороненка, О.Г. Шекери, О. В. Горбунової. – Київ : Заславський О. Ю., 2020. – 258 с. – (Сімейна медицина).
Martin-Hirsch P.P., Paraskevaidis E., Bryant A., Dickinson H.O., Keep S.L. Surgery for cervical intraepithelial neoplasia. Cochrane Database Syst Rev. 2010 Jun 16;(6):CD001318. doi: 10.1002/14651858.CD001318.pub2. Update in: Cochrane Database Syst Rev. 2013;12:CD001318.
Володько Н.А., Вінницька А.Б., Камінський В.В., Татарчук Т.Ф., Попков О.В., Білодід О.О., Боднар Т.М., [та ін.]. Український національний консенсус з лікування жінок після проходження первинного цервікального скринінгу. Доступно на: http://reproduct-endo.com/article/view/149296/148459
Національний канцер-реєстр України (НКРУ). Доступно на: http://ncru.inf.ua/
Siddiqui G., Kurzel R.B., Lampley E.C., Kang H.S., Blankstein J. Cervical dysplasia in pregnancy: progression versus regression post-partum. Int J Fertil Womens Med. 2001 Sep-Oct;46(5):278-80.
Origoni M., Salvatore S., Perino A., Cucinella G., Candiani M. Cervical Intraepithelial Neoplasia (CIN) in pregnancy: the state of the art. Eur Rev Med Pharmacol Sci. 2014;18(6):851-60.
Эпидемиологические аспекты, диагностика и лечение дисплазий шейки матки с учетом анализа ошибок в их распознавании: Метод. рекомендации / Е.Е. Вишневская, А.Е. Океанов, Т.М. Литвинова [и др.]. – Минск: НИИ ОМР, 2011. – 17 с.
Туманова Л.Є., Коломієць О.В., Бадзюк Н.П. Сучасні погляди на етіологію та патогенез фонових і передракових захворювань шийки матки у вагітних (огляд літератури). Здоровье женщины. 2014; 6(92):29-32.
Куликов И.А. Особенности патологи шейки матки во время беременности: автореф. на получение науч. степени канд. мед. наук: спец. 14.01.01. «Акушерство и гинекология»/ И.А. Куликов. – М., 2011. – 24 с.
Creasman W.T. Cancer and pregnancy. Ann N Y Acad Sci. 2001 Sep;943:281-6. doi: 10.1111/j.1749-6632.2001.tb03809.x.
Charkviani L., Charkviani T., Natenadze N., Tsitsishvili Z. Cervical carcinoma and pregnancy. Clin Exp Obstet Gynecol. 2003;30(1):19-22.
Скурятіна Н.Г. Наслідки вагітності в жінок після деструктивних методів лікування шийки матки. Акушерство. Гінекологія. Генетика. 2017; 3(2): 38 – 44.
Kostyuk I.Y. Вагітність і пологи у жінок, які перенесли різні методи лікування патології шийки матки. РЗЖ [інтернет]. 31, Серпень 2020 [цит. за 07, Жовтень 2021];2:35-9. доступний у: http://repro-health.com.ua/article/view/210958.
Arbyn M., Paraskevaidis E., Martin-Hirsch P., Prendiville W., Dillner J. Clinical utility of HPV-DNA detection: triage of minor cervical lesions, follow-up of women treated for high-grade CIN: an update of pooled evidence. Gynecol Oncol. 2005;99:7–11. doi: 10.1016/j.ygyno.2005.07.033.
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