TY - JOUR AU - Bolonska , A.V. AU - Sorokina, O.Yu. PY - 2021/09/30 Y2 - 2024/03/29 TI - Treatment and prophylaxis of moderate and severe bronchopulmonary dysplasia in premature neonates JF - Medicni perspektivi JA - Med. perspekt. VL - 26 IS - 3 SE - CLINICAL MEDICINE DO - 10.26641/2307-0404.2021.3.241961 UR - https://journals.uran.ua/index.php/2307-0404/article/view/241961 SP - 84-93 AB - <p>Bronchopulmonary dysplasia in premature neonates leads to physical and mental developmental disorders and behavioral problems and associated with frequent rehospitalizations and long hospital stay. Study objective: to study the predictors of bronchopulmonary dysplasia development in premature neonates in structure of intensive care. Study design: A retrospective cohort analysis was performed in 127 children recruited from two NICU of Dnipro between January 2016 to March 2020. Inclusion criteria: preterm neonates 28-32 gestation weeks with respiratory distress syndrome (RDS). Results demonstrated that every day of mechanical ventilation, supplemental oxygen with FiO<sub>2 </sub>more than 30% and cardiac drugs usage increased risk of bronchopulmonary dysplasia development by 15-20%. In conclusion, finding out predictors of bronchopulmonary dysplasia helps to improve&nbsp; and prudently use usual treatment regimens in premature neonates and decrease the frequency of moderate and severe bronchopulmonary dysplasia.</p> ER -