Helicobacter pylori infection: a modern view on virulence and pathogenicity factors

Authors

  • T.V. Sorokman MD, PhD, Professor, Department of pediatrics and medical genetics, Bukovinian State Medical University, Chernivtsi, Ukraine; е-mail: t.sorokman@gmail.com, https://orcid.org/0000-0001-7615-3466
  • N.O. Popelyuk PhD, Associate Professor at the Department of pediatrics, Bukovinian State Medical University, Chernivtsi, Ukraine, https://orcid.org/0000-0003-3961-7529
  • D.I. Kolesnik student of medical faculty 1, Bukovinian State Medical University, Chernivtsi, Ukraine,

DOI:

https://doi.org/10.22141/2312-413x.7.4.2019.178877

Keywords:

Helicobacter pylori, ureA/B, VacA, CagA, flaA, flaB, flaЕ, BabA, SabA, AlpA, AlpB, HopZ, Le, LPS factors, review

Abstract

The review considers the main pathogenicity factors of Helicobacter pylori: colonization factors, persistence factors and disease-causing factors. Modern data on mechanism of action, genotypic bases and significance in pathogenesis of diseases are presented.

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Published

2019-08-01

Issue

Vol. 7 No. 4 (2019)

Section

Review

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