Acellular dermal matrix in breast reconstruction surgery. First experience in Ukraine


  • A.V. Zhygulin LISOD Hospital of Israeli oncology, Kyiv, Ukraine,
  • A.E. Fedosov LISOD Hospital of Israeli oncology, Kyiv, Ukraine,
  • V.Ya. Palytsia LISOD Hospital of Israeli oncology, Kyiv, Ukraine,
  • V.S. Nedielchev LISOD Hospital of Israeli oncology, Kyiv, Ukraine,
  • D.K. Vinnytska LISOD Hospital of Israeli oncology, Kyiv, Ukraine,
  • Zvi Bernstein LISOD Hospital of Israeli oncology, Kyiv, Ukraine,



Background. Breast reconstruction after mastectomy is an important factor affecting patient’s quality of life. Mechanical and biological features of acellular dermal matrix (ADM) allows simplifying the breast reconstruction and achieving better functional and aesthetic results, especially for women


Background. Breast reconstruction after mastectomy is an important factor affecting patient’s quality of life. Mechanical and biological features of acellular dermal matrix (ADM) allows simplifying the breast reconstruction and achieving better functional and aesthetic results, especially for women with medium and large breast size. Objective: to present the first experience of breast reconstruction with ADM in Ukraine with the analysis of the technical aspects of surgeries, early and delayed surgical, oncological and functional results. Materials and methods. This work is the retrospective analysis of implant-based breast reconstruction with ADM in the Breast Unit of LISOD Hospital of Israeli Oncology. Results. Thirty-five operations were performed for 27 patients, 34 of them were immediate and one — delayed reconstruction. The average age of women was 44 (30–71) years. Therapeutic procedures were performed in 25 (73.5 %) cases, prophylactic — in 4 (11.8 %), symmetrised — in 5 (14.7 %). Eighteen (52.9 %) mastectomies were nipple-sparing. The average time of follow-up was 46 (6–84) months. Early complications such as ischemia and skin necrosis, infection, hematoma were detected in 11 (31.4 %) cases. Late complications such as infections and late seromas were observed in 4 (11.4 %) cases. Five (14.3 %) revisions were performed, 3 (8.6 %) implants were lost. Grade 3 capsular contracture was found in 5 (14.3 %) reconstructed breasts. Systemic recurrence occurred in 6 patients, 5 of them died. We had performed a survey about aesthetic and functional results in 21 (77.8 %) patients: 19 (90.5 %) were very satisfied and 2 (9.5 %) — were rather satisfied. No patients were unsatisfied. Conclusions. Despite the certain complications rate, the mechanical and biological features of ADM allow us to make an effective breast reconstruction even in patients with medium and large breasts. It provides for the further lipografting, and promotes good aesthetic and functional results after breast reconstruction.


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