ON THE ACOUSTO-MAGNETIC METHOD OF MEASURING THE ACOUSTIC RESISTANCE OF LOCAL AREAS OF THE BIOLOGICAL TISSUE
DOI:
https://doi.org/10.30837/ITSSI.2021.16.072Keywords:
acoustic resistance, biological tissue, acousto-magnetic method, electric voltage, ultrasoundAbstract
The subject of study in the article is the acoustic resistance of local areas of the biological tissues in vivo, depending on their pathology. The aim of the work is to develop a quantitative method for measuring the acoustic resistance of local areas of the biological tissue (substance) located inside the human body. The following tasks are solved in the article: development of scientific foundations of the acousto-magnetic method for measuring the acoustic resistance of local areas of the biological tissue; development of a remote method for measuring electrical voltage on the surface of the patient's skin, caused by acousto-magnetic impact on local areas of the tissue and determined by the value of acoustic resistance; calculation of the ratios binding the value of the acoustic resistance of the local areas of the tissue with the electric voltage on the measuring probes on the patient's skin, the values of the acoustic radiation power and the external constant magnetic field, as well as with the distance between the probes and the local area of the biological tissue; verification of the calculated ratios using the experimental determination of the acoustic resistance of the local area of the model biological tissue. The following methods were used: physical modeling of the biological tissue, physical and mathematical modeling of electrical properties of the local part of the biological tissue, calculation of electromagnetic and acoustic parameters of the tissue, experimental measurement of electric field strength excited in the local part of the biological tissue, verification of calculated relations by comparing them with experimental results. The following results were obtained: the scientific foundations of the acousto-magnetic method for the quantitative measurement of the acoustic resistance of local areas of the biological tissue were developed; a remote method for measuring the electric voltage on the surface of the patient's skin caused by the acousto-magnetic effect on local areas of the tissue and the determined value of the acoustic impedance was developed; relations were calculated connecting the value of the acoustic impedance of local areas of the tissue with the electric voltage on the measuring probes on the patient's skin, the values of the acoustic radiation power and external constant magnetic field, as well as the distance between the probes and the local area of the biological tissue; verification of the calculated ratios was carried out using the experimental determination of the acoustic resistance of the local area of the model biological tissue. Conclusions: The scientific foundations of the remote acousto-magnetic method of high-precision measurement of the acoustic resistance of local areas of human biological tissue, confirmed experimentally on model tissue samples, have been developed. The method can make it possible to reveal with high accuracy the functional relations of the measured local value of acoustic resistance with pathological changes in the tissue. At the same time, the influence of the human factor on the interpretation of the recorded values of acoustic resistance (which is characteristic of the traditional, mainly qualitative, rather than quantitative ultrasound method) is excluded, the information content and reliability of acoustic diagnostics are increased.
References
Oleinik, V. P. (2006), Fundamentals of Interaction of Physical Fields with Biological Objects [Osnovy vzaimodeystviya fizicheskikh poley s biologicheskimi ob"yektami], National Aerospace University – Kharkov Aviation Institute, 61 p.
Wang Shigang, Zhang Shunqi, Ma Ren, Yin Tao, Liu Zhipeng (2014), "A study of acoustic source generation mechanism of Magnetoacoustic Tomography", Computerized Medical Imaging and Graphics, No. 38, P. 42–48.
Elpiner, I. E. (1963), Ultrasound. Physicochemical and biological action [Ul'trazvuk. Fiziko-khimicheskoye i biologicheskoye deystviye], Moscow : Fizmatgiz, 420 p.
Bondarenko, I. S. (2017), "Magnetic hydrodynamics of the biological environment" ["Mahnytnaya hydrodynamyka byolohycheskoy sredy"], Promising directions of modern electronics, information and computer systems (MEICS-2017). Abstracts of reports at the II All-Ukrainian scientific-practical conference: November 22-24, 2017, Dnipro, P. 222–223.
Bondarenko, I. S., Avrunin, O. G., Bondarenko, S. I., Krevsun, A. V., Sorochan, E. N. (2018), "Experience and Prospects of Researching the Combined Action of Magnetic Field and Acoustic Radiation on Model and Real Biological Objects" ["Opyt i perspektivy issledovaniya sovmestnogo deystviya magnitnogo polya i akusticheskogo izlucheniya na model'nyye i real'nyye biologicheskiye ob"yekty"], Science and Technology: Mizhvuz. topics. zb. sciences. ave. VIP. 19 / DVNZ PDTU, Mariupol, PDTU, P. 138–150.
Landau, L. D., Lifshits, E. M. (1982), Continuous media electrodynamics [Elektrodinamika sploshnykh sred], Moscow, The science, Main editorial office of physical and mathematical literature, 616 p.
Kizimova, N. N. (1991), "Magnetohydrodynamic effects during blood movement" ["Magnitogidrodinamicheskiye effekty pri dvizhenii krovi"], Biophysics, Vol. 36, No. 1, P. 147.
Bondarenko, I., Avrunin, O., Gryshkov, O., Glasmacher, B. (2018), "Possibilities of joint application of acoustic radiation and direct magnetic field for biomedical research", International Journal of Bioelectromagnetism, Proceedings of the 11th International Conference on Bioelectromagnetism, 23-25 May 2018, Aachen, Germany, Vol. 20, No. 1, P. 66.
Avrunin, O. G., Bondarenko, I. S., Bondarenko, S. I., Kuzmenko, Y. V., Pinaieva, O. Yu., Kisała, P., Teleshova, A., Luganskaya, S. (2019), "Acoustic excitation of electric field in water solution NaCl", Przegląd elektrotechniczny, ISSN 0033-2097, R. 95 NR 4, P. 158–161.
Yavorskiy, B. M. Detlaf, A. A. (1985), Physics Handbook [Spravochnik po fizike], Moscow, Nauka, Main Edition of Physics and Mathematics Literature.
Bondarenko, I. S., Avrunin, O. G., Rakhimova, M. V., Bondarenko, S. I., Krevsun, A. V., Kulish, S. M. (2019), "Acoustomagnetic Registration of Magnetic Nanoparticles in a Liquid Medium", Telecommunications and Radio Engineering, Vol. 78 (8), P. 707–714.
Bondarenko, S. I., Avrunin, O. G., Bondarenko, I. S., Krevsun, A. V., Koverya, V. P., Rakhimova, M. V. (2020), "On the measurements of magnetic nanoparticle concentration in a biological medium using a superconducting quantum magnetometer", Low Temperature Physics/Fizika Nizkikh Temperatur, Vol.46, No. 11, P. 1287–1291.
Bondarenko, I., Avrunin, O. (2021), "On the excitation of local electric current in the biological environment", Innovative Technologies and Scientific Solutions for Industries, No. 1 (15), P. 106–112. DOI: https://doi.org/10.30837/ITSSI.2021.15.106
Elpiner, I. E. (1956), "Ultraacoustic parameters of organs and tissues and their importance in biology and medicine" ["Ul'traakusticheskiye parametry organov i tkaney i ikh znacheniye v biologii i meditsine"], Advances in modern biology, P. 143.
Frank, G. A. (2004), "Problems of morphological classification in the diagnosis of soft tissue neoplasms of the limbs and trunk" ["Problemy morfologicheskoy klassifikatsii v diagnostike novoobrazovaniy myagkikh tkaney konechnostey i tulovishcha"], Practical Oncology, Vol.5, No. 4, P. 231–236.
Dolgushin, B. I. , Kosyrev, V. Yu., Sinyukova, G. T. (2004), "Complex diagnostics of tumors of the biliopancreatoduodenal zone" ["Kompleksnaya diagnostika opukholey biliopankreatoduodenal'noy zony"], Practical Oncology, Vol. 4, No. 2, P. 77–84.
Poddubny, B. K., Gubin, A. N., Sholokhov, V. N., Vakurova, E. S. (2003), "Possibilities of laparoscopic intracavitary ultrasound (VUS) in a patient with stomach cancer" ["Vozmozhnosti laparoskopicheskogo vnutripolostnogo ul'trazvukovogo issledovaniya (VUZI) u bol'nogo rakom zheludka"], Opportunities of modern oncologists in the diagnosis and treatment of malignant diseases, Moscow, P. 43.
Glybachko, P. V., Chekhonatskaya, M. L., Priezzheva, V. N. (2007), "Transrectal ultrasound examination with the use of Doppler mapping in prostate cancer" ["Transrektal'noye ul'trazvukovoye issledovaniye s primeneniyem dopplerovskogo kartirovaniya pri rake predstatel'noy zhelezy"], Topical issues of urology and nephrology, Sat. scientific works, Engels, P. 82–84.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Our journal abides by the Creative Commons copyright rights and permissions for open access journals.
Authors who publish with this journal agree to the following terms:
Authors hold the copyright without restrictions and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (CC BY-NC-SA 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-commercial and non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their published work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as earlier and greater citation of published work.