Liudas Ivanauskas

Liudas Ivanauskas E-mail
Lithuanian University of Health Science, Литва


Medical Academy, Faculty of Pharmacy

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Профессиональные (научные) интересы: the scientific work area involves investigations into the chemical composition of plant origin raw materials and herbal preparations. The area of research covers development, optimisation and application of HPLC methods. New modern informative analysis methods characterised by high selectivity and informational capability are being developed and validated for the chemical evaluation of the groups of biologically active compounds in raw materials of plant origin (The raw material of ginkgo, ginseng, St. John's wort, blueberry, goldenrod, ginkgo, ginseng, oregano, thyme, potatoes, buckwheat, bee products were analyzed). HPLC post-column assays are developed and optimised. Besides, the scientific research on optimisation of equipment complementation and system constitution for the screening of various antioxidants of plant origin, for the evaluation of their distribution in different plant organs, and for quality control by antioxidant activity is performed. DPPH and ABTS post-column assays are optimised for the rapid identification and activity determination of antioxidants in complex mixtures after the chromatographical separation of analytes. The reseach evaluating antioxidant activity of phenolic compounds in the extracts of herbal raw materials is conducted as well.


Основные публикации:

1. Klimaviciute, R. Complexes of dextran sulfate and anthocyanins from Vaccinium myrtillus: Formation and stability [Text] / R. Klimaviciute, V. Navikaite, V. Jakstas, L. Ivanauskas // Carbohydrate Polymers. – 2015. – Vol. 129. – P. 70–78. doi: 10.1016/j.carbpol.2015.04.038

2. Radusiene, J. Assessment of phenolic compound accumulation in two widespread goldenrods [Text] / J. Radusiene, M. Marska, L. Ivanauskas, V. Jakstas, B. Karpaviciene // Industrial Crops and Products. – 2015. – Vol. 63. – P. 158–166. doi: 10.1016/j.indcrop.2014.10.015

3. Rimkiene, L. Optimization of a CUPRAC-Based HPLC Postcolumn Assay and Its Applications for Ginkgo biloba L. Extracts [Text] / L. Rimkiene, L. Ivanauskas, A. Kubiliene, K. Vitkevicius, G. Kiliuviene, V. Jakstas // Journal of Analytical Methods in Chemistry. – 2015. – Vol. 2015. – P. 1–7. doi: 10.1155/2015/280167

4. Brazinskiene, V. Effect of farming systems on the yield, quality parameters and sensory properties of conventionally and organically grown potato (Solanum tuberosum L.) tubers [Text] / V. Brazinskiene, R. Asakaviciute, A. Miezeliene, G. Alencikiene, L. Ivanauskas, V. Jakstas et. al. // Food Chemistry. – 2014. – Vol. 145. – P. 903–909. doi: 10.1016/j.foodchem.2013.09.011

5. Spadiene, A. Antioxidant effects of Camellia sinensis L. extract in patients with type 2 diabetes [Text] / A. Spadiene, N. Savickiene, L.Ivanauskas, V. Jakstas, A. Skesters, A. Silova, H. Rodovicius // Journal of Food and Drug Analysis. – 2014. – Vol. 22, Issue 4. – P. 505–511. doi: 10.1016/j.jfda.2014.04.001

6. Camas, N. Altitudinal changes in the content of bioactive substances in Hypericum orientale and Hypericum pallens [Text] / N. Camas, J. Radusiene, L. Ivanauskas, V. Jakstas, C. Cirak // Acta Physiologiae Plantarum. – 2013. – Vol. 36, Issue 3. – P. 675–686. doi: 10.1007/s11738-013-1446-z

7. Camas, N. Chemical composition of Hypericum species from the Taeniocarpium and Drosanthe sections [Text] / N. Camas, J. Radusiene, L.Ivanauskas, V. Jakstas, S. Kayikci, C. Cirak // Plant Systematics and Evolution. – 2013. – Vol. 300, Issue 5. – P. 953–960. doi: 10.1007/s00606-013-0934-3