Lucjusz Zaprutko

Lucjusz Zaprutko E-mail
Poznan University of Medical Sciences, Польша

Professor

Pharmaceutical Faculty


Профиль Scopus: ссылка

ResearcherGate: ссылка

Профессиональные (научные) интересы: Medicinal chemistry, Organic chemistry, Natural compounds, Triterpenes, Isoprenoids, Heterocyclic compounds, Azoles, Cosmetics, Fragrances

 

Основные публикации:

1. Żwawiak, J. Reactions of Nucleophilic Substitution in Bicyclic Nitroimidazodihydrooxazoles [Text] / J. Żwawiak, L. Zaprutko // Journal of Heterocyclic Chemistry. – 2014. – Vol. 51, Issue 5. – P. 1463–1467. doi: 10.1002/jhet.1907

2. Bednarczyk-Cwynar, B. Recent advances in synthesis and biological activity of triterpenic acylated oximes [Text] / B. Bednarczyk-Cwynar, L. Zaprutko // Phytochemistry Reviews. – 2014. – Vol. 14, Issue 2. – P. 203–231. doi: 10.1007/s11101-014-9353-5

3. Lisiak, N. Methyl 3-hydroxyimino-11-oxoolean-12-en-28-oate (HIMOXOL), a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MDA-MB-231 breast cancer cells [Text] / N. Lisiak, A. Paszel-Jaworska, B. Bednarczyk-Cwynar, L. Zaprutko, M. Kaczmarek, M. Rybczyńska // Chemico-Biological Interactions. – 2014. – Vol. 208. – P. 47–57. doi: 10.1016/j.cbi.2013.11.009

4. Bednarczyk-Cwynar, B. Beckmann rearrangement of oxime obtained from oleanolic acid. Structure elucidation of the initial oxime [Text] / B. Bednarczyk-Cwynar, L. Zaprutko, A. Froelich // Journal of Molecular Structure. – 2013. – Vol. 1053. – P. 115–121. doi: 10.1016/j.molstruc.2013.09.006

5. Loboda, A. Targeting Nrf2-Mediated Gene Transcription by Triterpenoids and Their Derivatives [Text] / A. Loboda, E. Rojczyk-Golebiewska, B. Bednarczyk-Cwynar, L. Zaprutko, A. Jozkowicz, J. Dulak // Biomolecules and Therapeutics. – 2012. – Vol. 20, Issue 6. – P. 499–505. doi: 10.4062/biomolther.2012.20.6.499

6. Kaminskyy, D. Synthesis of new potential anticancer agents based on 4-thiazolidinone and oleanane scaffolds [Text] / D. Kaminskyy, B. Bednarczyk-Cwynar, O. Vasylenko, O. Kazakova, B. Zimenkovsky, L. Zaprutko, R. Lesyk // Medicinal Chemistry Research. – 2011. – Vol. 21, Issue 11. – P. 3568–3580. doi: 10.1007/s00044-011-9893-9

7. Bednarczyk-Cwynar, B. The analgesic and anti-inflammatory effect of new oleanolic acid acyloxyimino derivative [Text] / B. Bednarczyk-Cwynar, L. Zaprutko, J. Marciniak, G. Lewandowski, M. Szulc, E. Kaminska et. al // European Journal of Pharmaceutical Sciences. – 2012. – Vol. 47, Issue 3. – P. 549–555. doi: 10.1016/j.ejps.2012.07.017