Design of consrtuction and hydrodynamic modeling in a roller bioreactor with surface cultivation of cell cultures

Authors

DOI:

https://doi.org/10.15587/2313-8416.2017.107176

Keywords:

bioreactor, cell cultivation, computer modeling, hydrodynamics, shear stress, immobilized eukaryotic cells

Abstract

Design of construction of a bioreactor for the cultivation of cell cultures is developed and computer modeling of hydrodynamic apparatus is carried out. The field of velocity vectors of the fluid in the apparatus, the shear rate for a fluid, the fluid shear stress in the area of cell immobilization are obtained. The obtained results confirm the technological effectiveness of bioreactor construction and can be used in the design of pilot samples of the apparatus

Author Biographies

Vladyslav Shybetskiy, National Technical University of Ukraine «Igor Sikorsky Kyiv Polytechnic Institute» Peremohy ave., 37, Kyiv, Ukraine, 03056

PhD, Senior Lecturer

Department of Biotechnology and Engineering

Serhii Semeniuk, National Technical University of Ukraine «Igor Sikorsky Kyiv Polytechnic Institute» Peremohy ave., 37, Kyiv, Ukraine, 03056

Department of Biotechnology and Engineering

Sergiy Kostyk, National Technical University of Ukraine «Igor Sikorsky Kyiv Polytechnic Institute» Peremohy ave., 37, Kyiv, Ukraine, 03056

PhD, Assistant

Department of Biotechnology and Engineering

References

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Published

2017-07-31

Issue

Section

Technical Sciences