DOI: https://doi.org/10.15587/2313-8416.2014.35085

About a mechanism of the influence of shear stress for viscosity of the blood in vessels of small diameter

Лев Николаевич Катюхин

Abstract


It is proposed a physiological and experimentally confirmed explanation of Fåhraeus-Lindqvist-effect in capillaries using the profile analyses of osmotic deformability of red blood cells. It was shown the dose-dependent change of the erythrocytes deformability in the stage of isotropic spheres after forming artificial water pores (nystatin) and occlusion (PbCl2) of available pores. The Sigma-effect reducing of hematocrit and viscosity in a shear flow of blood through the vessels of a small diameter was conditioned by the interchange of liquid phase between the erythrocyte and the plasma.


Keywords


sigma-effect; viscosity; erythrocytes; deformability; water pores; shear stress

References


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Tillmann, W. (1986). Reduced deformability of erythrocytes as a common denominator of hemolytic anemias. Wien. Med. Wochenschr., 136, 14–16.


GOST Style Citations


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