Immunohistochemical structural pecularities of uterine tube of fetuses with signs of intrauterine infection
Keywords:fetus, pregnancy, intrauterine infection, connective tissue, primary infertility
Aim - immunohistochemical detection of structural features of the uterine tubes of fetuses with signs of intrauterine infection.
Methods: anthropometric, macroscopic, organometric, histological, immunohistochemical, statistical.
Object of research - the uterine tubes of antenatal dead fetuses. The control group consisted of 25 fetuses of healthy mothers; the comparison group is 15 fetuses with signs of intrauterine infection. Fetal infection confirmed by laboratory methods; the presence of TORCH infections, cytomegalovirus, herpes infection and chlamydial infection is determined.
Results: indicators of weight and body length of the fetus of the comparison group were significantly reduced. Unidirectional changes are established in the definition of the mass and the length of the uterine tubes of fetuses with signs of intrauterine infection. Massive growth of connective tissue in the mucosa, the mucous membrane and muscle membrane of wall of the uterine tube of fetus in the comparison group is shown by histological methods. Violation of collagen formation in the connective tissue in the uterine tubes of fetuses with signs of intrauterine infection is found by immunohistochemistry method.
Conclusions: The reduction of anthropometric and organometric indicators in fetuses of comparison group is shown. Sclerosis and atrophy, as well as violations of collagen-synthesizing function are predominated in the main structural components of the wall of the uterine tube of fetuses in the comparison group. The revealed changes in the future ontogenesis may lead to the development of primary infertility
Znamenskaya, T. K. (2011). Development Priorities of perinatal services in Ukraine. Neonatologіya, hіrurgіya that perinatal medicine, 2, 6–11.
Bashmakova, N. V., Kravchenko, E. N., Lopushansky, V. G. (2008). Role predicting intrapartum risk factors. Obstetrics and Gynecology, 3, 57–61.
Apresian, S. V., Radzinsky, V. E. (2009). Pregnancy and childbirth at extragenital diseases. Moscow: GEOTAR – Media, 457.
Shunko, J. (2011). Vprovadzhennya kontseptsіi away rozvitku perinatalnoi in care to the Ukrainі. Neonatologіya, hіrurgіya that perinatal medicine, 1, 10–16.
Belova, O. (2009). forecast rozvitku dіtey s duzhe maloyu masoyu tіla at narodzhennі: mіzhnarodny i vіtchiznyany dosvіd. [ST. materіalіv XIII Congress medichnogo studentіv that young vchenih]. Ternopil, 101.
Subbotin, M. J., Laguchev, S., Hovhannisyan, Т. (1954). Histological technique. Moscow: State Publishing House of the medical literature "Medgiz", 167.
Kosharnaya, V. V., Shatorna, V. F. (2009). Vikoristannya іmunogіstohіmіchnih metodіv doslіdzhennya in embrіologіi. Patologіya, 2, 66–69.
Gubіna-Vakulіk, G. I., Markovsky, V. D., Sorokіna, I. V., Kіhtenko, O. V., Kuprіyanova, L. S., Sidorenko, R. V. (2009). Patent for korisnu model "Sposіb kіlkіsnogo viznachennya vmіstu antigen in bіologіchnih tkaninah», u200906730.
Atramentova, L. A., Utevskaya, О. М. (2008). Statistical Methods in Biology. Gorlovka, 247.
Dankovich, N. O. (2004). Osoblivostі somatichnoi zahvoryuvanostі, rozumovogo, psihoemotsіonalnogo that fіzichnogo rozvitku dіvchatok, yakі had been born іz zatrimkoyu vnutrіshnoutrobnogo rozvitku. Pedіatrіya, obstetrics that gіnekologіya, 1, 138–140.
Klemenov, A. V., Tkacheva, A. V., Vertkin, A. L. (2004). Connective tissue dysplasia and pregnancy. Therapeutic archive, 11, 80–83.
Nazarenko, L. G., Neelova, O. V. (2005). Spoluchnotkaninnі displazіi - a problem that perinatologіi Suchasna Obstetrics. Pedіatriya, obstetrics that gіnekologіya, 6, 93–96.
Ohapkіna, O. V. (2011). Vіko statevі osoblivostі klіnіchnogo perebіgu displastikozalezhnoi patologіi in dіtey. News of the problems i bіologіi medicine, 2, 147–149.
Copyright (c) 2015 Лариса Сергеевна Куприянова
This work is licensed under a Creative Commons Attribution 4.0 International License.
Our journal abides by the Creative Commons CC BY copyright rights and permissions for open access journals.
Authors, who are published in this journal, agree to the following conditions:
1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the journal under the terms of a Creative Commons CC BY, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this journal.
2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form in which it has been published by the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.