The index of abdominal obesity as a marker of disorder of blood serum triglicerides fatty-acid spectrum in patients with diabetes mellitus type 2
Keywords:visceral obesity index, diabetes mellitus type 2, triglyceride, fatty acids
Aim of research. To determine the possibility to use the visceral obesity index (VOI) for diagnostics of lipid metabolism disorders in patients with diabetes mellitus (DM) type 2 on the base of the study of adipose tissue and triglycerides fatty acids content in the blood serum of patients.
Materials and methods. There were determined the body mass, height, waist size, blood serum lipid fraction (triglycerides, LPHD), calculated the body mass index and VOI in 19 patients with DM type 2 older then 50 years. There were determined the content of fatty acids (palmitic С16:0, stearin С18:0, oleic С18:1 and linoleic С18:2) in triglycerides using the method of liquid-gas chromatography.
Results. Examined patients were separated into 3 groups according to VOI value. There was detected that the higher VOI values in patients with diabetes mellitus type 2 (upper tertile) were associated with the most intensive unfavorable changes of the fatty-acid spectrum of triglyceride fraction in the blood serum at the expense of an increase of saturated palmitic and stearin fatty acids fraction and decrease of unsaturated oleic and linoleic acids content. There were revealed the correlations between VOI and the levels of saturated and unsaturated triglyceride fatty acids.
Conclusion. The calculation of VOI in patients with DM type 2 can be the useful indicator of the lipid metabolism disorder, especially the deviations of triglyceride fatty-acid spectrum
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