Determination of the level of spontaneous and induced chromosome abnormalities in peripheral blood lymphocytes of patients with juvenile rheumatoid arthritis
DOI:
https://doi.org/10.15587/2313-8416.2016.60318Keywords:
chromosomal aberrations, juvenile rheumatoid arthritis, peripheral blood lymphocytes, model mutagenAbstract
It has been found increase the spontaneous level of chromosomal disorders (by 2.6 times) in the blood lymphocytes of patients with juvenile rheumatoid arthritis, as compared with healthy. Our study has established the increase level of chromosomal abnormalities in the blood lymphocytes in vitro depending on the clinical course options, the activity of the pathological process, applied therapy and patient’s age. Model mutagen caused an increase in the general level of chromosomal aberrationsReferences
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