Toxicity evaluation of gold and diamond nanoparticles

Authors

  • Наталия Федоровна Беляева Institute of Biomedical Chemistry 10-8 Pogodinskaya str., Moscow, Russia, 119121, Russian Federation
  • Константин Владимирович Золотарёв Institute of Biomedical Chemistry 10-8 Pogodinskaya str., Moscow, Russia, 119121, Russian Federation
  • Валентина Николаевна Каширцева Institute of Biomedical Chemistry 10-8 Pogodinskaya str., Moscow, Russia, 119121, Russian Federation
  • Оксана Сергеевна Дружиловская Institute of Biomedical Chemistry 10-8 Pogodinskaya str., Moscow, Russia, 119121, Russian Federation
  • Дамир Вячеславович Игнатов Limited Liability Company "EcoBioFarm" B. Kozlovsky per., D. 11, p. 1, Moscow, Russia, 107078, Russian Federation
  • Ольга Михайловна Ипатова Institute of Biomedical Chemistry 10-8 Pogodinskaya str., Moscow, Russia, 119121, Russian Federation
  • Марина Викторовна Михайлова Institute of Biomedical Chemistry 10-8 Pogodinskaya str., Moscow, Russia, 119121, Russian Federation

DOI:

https://doi.org/10.15587/2313-8416.2014.34227

Keywords:

nanoparticles, nanogold, nanodiamonds, toxic effects, model systems, zebrafish, embryos, larvae

Abstract

Toxicity of gold and diamond nanoparticles in zebrafish (Danio rerio) early life stages has been assessed. No toxic action of nanogold has been found. At the same time, nanodiamonds caused lethal effects (LC50 is 104±18 mg/L) as well as developmental abnormalities during 7 days.

Author Biographies

Наталия Федоровна Беляева, Institute of Biomedical Chemistry 10-8 Pogodinskaya str., Moscow, Russia, 119121

PhD, Senior Researcher

Laboratory of environmental biotechnology

Константин Владимирович Золотарёв, Institute of Biomedical Chemistry 10-8 Pogodinskaya str., Moscow, Russia, 119121

Junior Researcher

Laboratory of environmental biotechnology

Валентина Николаевна Каширцева, Institute of Biomedical Chemistry 10-8 Pogodinskaya str., Moscow, Russia, 119121

Junior Researcher

Laboratory of Nanomedicines 

Оксана Сергеевна Дружиловская, Institute of Biomedical Chemistry 10-8 Pogodinskaya str., Moscow, Russia, 119121

PhD, Researcher

Laboratory of Nanomedicines 

Дамир Вячеславович Игнатов, Limited Liability Company "EcoBioFarm" B. Kozlovsky per., D. 11, p. 1, Moscow, Russia, 107078

Junior Researcher

Ольга Михайловна Ипатова, Institute of Biomedical Chemistry 10-8 Pogodinskaya str., Moscow, Russia, 119121

Doctor of Biological Sciences, Head of Laboratory

Laboratory of Nanomedicines

Марина Викторовна Михайлова, Institute of Biomedical Chemistry 10-8 Pogodinskaya str., Moscow, Russia, 119121

PhD, Head of Laboratory

Laboratory of Nanomedicines 

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Published

2014-12-22

Issue

Vol. 5 No. 4(5) (2014)

Section

Medical

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Copyright (c) 2014 Наталия Федоровна Беляева, Константин Владимирович Золотарёв, Валентина Николаевна Каширцева, Оксана Сергеевна Дружиловская, Дамир Вячеславович Игнатов, Ольга Михайловна Ипатова, Марина Викторовна Михайлова

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