Cytokine status of patients with acute sluggish odontogenic osteomyelitis of the jaw

Authors

  • Неонилла Гавриловна Баранник Zaporozhie Medical Academy of Postgraduate Education, Ukraine City Clinical Hospital of Emergency and Ambulance Zaporozhye, st. Victory 80, 69005, GU "GKBE and NSR, Ukraine
  • Сурен Диасович Варжапетян Zaporozhie Medical Academy of Postgraduate Education, Ukraine City Clinical Hospital of Emergency and Ambulance Zaporozhye, st. Victory 80, 69005, GU "GKBE and NSR", Ukraine

DOI:

https://doi.org/10.15587/2313-8416.2015.36524

Keywords:

immunological status, acute odontogenic osteomyelitis of the jaws, interleukins

Abstract

The content of IL-1β in the serum level was 1,823±0,300 (p<0.001), which is approximately 14.7 times the value of this indicator in healthy individuals - control group (0,124±0,026). The concentration of TNFα in the blood of healthy individuals was 0,196±0,023, while in patients with acute odontogenic osteomyelitis occurs without acute clinical symptoms, observed an increase in the corresponding rate to 2,752±0,624 (p<0.001), almost 14 times. In the study group, it was also a sevenfold increase in the synthesis of IL-6 (22,224±8,244; p<0.001) compared with the control group (3,158±0,214).

The content of anti-inflammatory factors, immunological protection of organism (IL-4) in patients with odontogenic osteomyelitis at admission was 0,462±0,064, which was a statistically significant increase (p>0,05) compared with those in the control group – 0,416±0,058

Author Biographies

Неонилла Гавриловна Баранник, Zaporozhie Medical Academy of Postgraduate Education, Ukraine City Clinical Hospital of Emergency and Ambulance Zaporozhye, st. Victory 80, 69005, GU "GKBE and NSR

MD, professor

Head of Department of Surgical and therapeutic dentistry

Сурен Диасович Варжапетян, Zaporozhie Medical Academy of Postgraduate Education, Ukraine City Clinical Hospital of Emergency and Ambulance Zaporozhye, st. Victory 80, 69005, GU "GKBE and NSR"

Assistant, PhD

Department of Surgical and therapeutic dentistry

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Published

2015-01-27

Issue

Section

Medical