Pharmacotherapeutic directions of iodine herbal remedies use for different groups of thyroid deseases treatment

Authors

  • Інна Миколаївна Владимирова National University of pharmacy, Ukraine
  • Вікторія Акоповна Георгіянц National University of Pharmacy 53 Pushkinska str., Kharkiv, Ukraine, 61002, Ukraine

DOI:

https://doi.org/10.15587/2313-8416.2015.54987

Keywords:

iodine deficiency diseases, hypothyroidism, hyperthyroidism, natural extracts, iodine-containing compounds, use

Abstract

Recently, the increase of endocrine diseases is observed worldwide. Diabetes mellitus and thyroid gland pathologies are the most widespread. Endocrine diseases can be acute or chronic. In some cases, they are life threatening.

There are different reasons of thyroid gland pathologies development. Both poor nutrition and poor quality water use, and unfavorable environmental conditions, including radiation, are among them. Iodine deficiency is determined to be one of the main reasons of these diseases.

Aim. Determination of the pharmacotherapeutic directions of iodine herbal remedies use for different groups of thyroid diseases treatment.

Methods. Thyroid stimulating action determination (primary screening and model pathology) has been carried out by the method of “goiter reaction” in rats at the Central Scientific-Research Laboratory of National University of Pharmacy. Determination of thyroid hormone blood level in rats has been carried out at the Laboratory of Radioactive Endocrinology of the State Institution “Grigoriev Institute for medical Radiology NAMS of Ukraine”.

Results. According to the research results generalization, correctness of developed algorithms was confirmed; peculiarities of the influence on pathological processes in thyroid, and prospects of implementation and use of herbs and herbal remedies for thyroid diseases prevention and treatment were determined.

Conclusion. Obtained experimental data are actual for the modern medicine, and new scientific research, specifying their place in etiology, pathogenesis and peculiarities of clinical course of many diseases, will improve the efficiency of treatment and prevention of thyroid diseases

Author Biographies

Інна Миколаївна Владимирова, National University of pharmacy

Doctor of pharmaceutical science, associate professor, associate professor of department of quality, standartization and sertification of drugs

 

GoogleScholar profile: link

ID ORCID: http://orcid.org/0000-0002-6584-4840

Professional (scientific) interests: development of composition, technology and standartization of plant-based drugs; standartization of medicinal raw materials and development of monograph in the State Pharmacopoeia of Ukraine

 

Selected Publications:

1. Kravchenko, V. N., Georgijanc, V. A., Vladimirova, I. N., Kononenko, A. G., Orlova, V. A., Shherbak, E. A. (2014). Vlijanie lekarstvennyh rastenij na uroven' jodsoderzhashhih gormonov shhitovidnoj zhelezy v krovi u krys. Biologicheskij zhurnal Armenii, 4 (66), 17–21.

2. Vladymyrova, I. M. (2014). Morfologo-anatomichna standartyzacija Genista tinctorial. Fitoterapija, 4, 58–61.

3. Vladymyrova, I. M. (2014). Rozrobka metodologichnyh pidhodiv do stvorennja fitoterapevtychnyh zasobiv pry gipertyreozi. Farmacevtychnyj chasopys, 4, 51–57.

4. Kravchenko, V. N., Georgijanc, V. A., Vladimirova, I. N., Shherbak, E. A., Orlova, V. A., Kononenko, A. G. (2014). Izuchenie vlijanija lekarstvennyh rastenij na funkciju shhitovidnoj zhelezy. Vestnik VGMU, 13 (4), 149–154.

5. Vladimirova, I. N., Georgijanc, V. A. (2013). Mass-spektrometricheskoe opredelenie biologicheski aktivnyh soedinenij zjuznika evropejskogo. Nauchnye vedomosti. Serija Medicina. Farmacija, 25 (168(24)), 213–216.

6. Vladymyrova, I. M. (2012). Vyznachennja tropanovyh alkaloi'div u travi netreby zvychajnoi'. Farmacevtychnyj chasopys, 4, 84–86.

7. Vladymyrova, I. M., Kotova, E. E., Georgijanc, V. A., Kotov, A. G. (2011). Analiz i farmakopejna standartyzacija syrovyny—laminarii' slani. Upravlinnja, ekonomika ta zabezpechennja jakosti v farmacii', 5 (19), 4–8.

Вікторія Акоповна Георгіянц, National University of Pharmacy 53 Pushkinska str., Kharkiv, Ukraine, 61002

Professor, Doctor of pharmaceutical sciences, head of the Department of Pharmaceutical chemistry 

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Published

2015-11-29

Issue

Section

Pharmaceutical Sciences