Assessment of splenic blood flow in patients with the compensated and decompensated course of cirrhosis

Authors

  • Алий Саитович Тугушев Zaporozhye state medical university; Sedov St., 3, Zaporozhye, Ukraine, 69035, Ukraine
  • Виталий Викторович Вакуленко Zaporozhye State Medical University 3 Sedova str., Zaporozhye, Ukraine, 69035, Ukraine
  • Ольга Степановна Черковская Zaporozhye State Medical University 3 Sedova str., Zaporozhye, Ukraine, 69035, Ukraine
  • Дмитрий Иванович Михантьев SD «Local clinical hospital on the station Zaporozhye-2 of the Pridneprovsky railway» 21 Chumachenko str., Zaporozhye, Ukraine, 69104, Ukraine
  • Вячеслав Васильевич Нешта SD «Local clinical hospital on the station Zaporozhye-2 of the Pridneprovsky railway» 21 Chumachenko str., Zaporozhye, Ukraine, 69104, Ukraine
  • Павел Иванович Потапенко SD «Local clinical hospital on the station Zaporozhye-2 of the Pridneprovsky railway» 21 Chumachenko str., Zaporozhye, Ukraine, 69104, Ukraine

DOI:

https://doi.org/10.15587/2313-8416.2015.45162

Keywords:

cirrhosis, splenomegaly, splenic blood flow, ultrasound scanning, dopplerography

Abstract

Splenomegaly, increased splenic blood flow are the specific characteristics of the natural course of cirrhosis. But an importance of these alienations is inadequately appreciated when choosing methods of correction the portal hypertensia syndrome.

Aim of the study. To assess the splenic blood flow in patients with compensated and decompensated course of cirrhosis.

Materials and methods.190 patients with cirrhosis were under surveillance: 123 had the gastrointestinal bleeding, 67 – the refractory ascites. 84 patients died during surveillance. The surveillance lasted from 2-3 weeks to 2,5 -3 years.

All patients underwent reiterated ultrasound study of an abdominal cavity. The dimensions of spleen, diameter of hepatic and splenic vessels were assessed; the qualitative and quantitative characteristics of blood flow in hepatic and splenic arteries, portal and splenic veins were defined.

Result of the study. All cirrhosis patients have the different degree of splenomegaly with increase of volumetric blood flow in splenic artery and vein in 1,3 and 3,2 times respectively. At the decompensation of disease on the background of decrease of the blood flow in portal vein, hepatic and splenic arteries, the blood flow in splenic vein practically didn’t change. The ratio between the volumetric blood flow in splenic vein and the portal one at decompensation of disease increased from 65,5±18,0 % to 99,1±27,0 %, while the norm is 43,2±15,0 % (р < 0,01), that can be the one of prognostic indications of the complications development.

Conclusions. The natural course of cirrhosis characterizes by increase of the splenic blood flow relative to the portal one when transition from the compensated state to the decompensated one, that can be one of the factors of increase of the portal pressure and hemodynamic causes of the complications development that must be taken into account choosing method of correction the syndrome of portal hypertensia

Author Biographies

Алий Саитович Тугушев, Zaporozhye state medical university; Sedov St., 3, Zaporozhye, Ukraine, 69035

Candidate of Medical Science, Assistant

Department of faculty surgery

Виталий Викторович Вакуленко, Zaporozhye State Medical University 3 Sedova str., Zaporozhye, Ukraine, 69035

Candidate of Medical Science, Assistant

Department of Surgery

Ольга Степановна Черковская, Zaporozhye State Medical University 3 Sedova str., Zaporozhye, Ukraine, 69035

Candidate of Medical Science, Assistant

Department of Surgery

Дмитрий Иванович Михантьев, SD «Local clinical hospital on the station Zaporozhye-2 of the Pridneprovsky railway» 21 Chumachenko str., Zaporozhye, Ukraine, 69104

Managing surgical office

Вячеслав Васильевич Нешта, SD «Local clinical hospital on the station Zaporozhye-2 of the Pridneprovsky railway» 21 Chumachenko str., Zaporozhye, Ukraine, 69104

Candidate of Medical Sciences doctor-intern of surgical branch

Павел Иванович Потапенко, SD «Local clinical hospital on the station Zaporozhye-2 of the Pridneprovsky railway» 21 Chumachenko str., Zaporozhye, Ukraine, 69104

attending physician of surgical office

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Published

2015-06-29

Issue

Section

Medical