The perspective of polymers use as excipients in solid dosage forms production
DOI:
https://doi.org/10.15587/2313-8416.2015.54891Keywords:
technology, solid dosage forms, tablets, excipients, polymers, physical and chemical properties, useAbstract
Rational and scientifically grounded excipients selection is quite essential to increase the remedies competitiveness on the market. Excipients significantly affect the active pharmaceutical ingredients bioavailability and promote pharmacological activity. In development and upgrading of the solid dosage forms technology high molecular weight organic compounds, allowing creating drugs with predicted biopharmaceutical and technological parameters play a leading role recently. A wide range of new polymers allows creating the optimum conditions for implementation of activity of remedies with different chemical structures and action directions. The use of new, universal high molecular weight organic compounds create prerequisites for technological process optimization.
Aim. To determine modern polymers used in pharmacy, their physical and chemical properties, and the area of use.
Conclusion. Therefore, excipients diversification due to new generation of high molecular weight organic compounds create new possibilities for tableting process improvement and obtaining high quality remedies
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Copyright (c) 2015 Інна В’ячеславівна Ковалевська, Олена Анатоліївна Рубан
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