Assessment of the reaction of the cardiovascular system to dosed physical activity of patients with metabolic syndrome under the influence of the use of physical therapy


  • Yuliya Kalmykova
  • Sergey Kalmykov
  • Natalia Orshatska


metabolic syndrome, Martine-Kushelevsky test, physical therapy, women


Purpose: study of the reaction of the cardiovascular system to dosed physical activity of patients with metabolic syndrome in the process of applying a physical therapy program.

Material & Methods: 28 young women with metabolic syndrome took part in the study, CG – 14 women, MG – 14 women. The mean age of the patients with MG was 31,49±0,71 years, and the CG was 31,06±0,57 years. In order to determine and assess the tolerance of the cardiovascular system to dosed physical activity in the examined patients, the Martine-Kushelevsky test was used.

Results: analyzed and summarized the results of a study of the reaction of the cardiovascular system to dosed physical activity according to the Martin-Kushelevsky test. According to the initial examination in the main and control groups, the indicator of the quality of the reaction according to the Martine-Kushelevsky test was less than normal, which indicates an unsatisfactory reaction of the cardiovascular system of patients to physical activity. After applying the physical therapy program, LRP increased in the main group from 0,40±0,17 to 0,54±0,01 c. u. (by 35,0%), in the control – from 0,41±0,17 to 0,49±0,12 c. u. (by 19,5%).

Conclusions: the analysis of the reaction quality indicators in patients of the main and control groups showed that they were better at repeated examination in the main group of patients after applying the author's physical rehabilitation program.


Baranovskaya V.V., Zykova A.A. & Sinitsyna A.V. (2005), Metabolicheskiy sindrom, Ye.I. Sokolov (red.), Moscow. (in Russ.)

Belaya, N.A. (2001), Lechebnaya fizkultura i massazh [Physical therapy and massage], Sovetskiy sport, Moscow. (in Russ.)

Verbov, A.F. (2006), Alphabet of massage, Moscow. (in Russ.)

Verbov, A.F. (2002), The Basics of Massage Therapy, St. Petersburg. (in Russ.)

Universal Declaration on Bioethics and Human Rights (Adopted on 10/19/2005 at the 33rd session of the General Conference of UNESCO). United Nations Educational, Scientific and Cultural Organization, available at: (in Russ.)

Didenko, V.A. (2009), "Metabolicheskiy sindrom X: istoriya voprosa i etiopatogenez", Laborator. Med, No. 2, pp. 49-56. (in Russ.)

Iefimenko, P.B. (2013), Tekhnika ta metodyka klasychnoho masazhu [Technique and method of classical massage], KhNADU, Kharkiv. (in Ukr.)

Kalmykov, S.A. (2012), Complex physical rehabilitation of persons of mature age, patients with type 2 diabetes mellitus, at the polyclinic stage: Dissertation of the candidate of medical sciences, Dnipropetrovsk Medical Academy of Health Ministry of Ukraine, 240 p. (in Ukr.)

Kalmykov, S.A. (2010), Kompleksna fizychna reabilitatsiya khvorykh na tsukrovyy diabet 2-ho typu [Complex physical rehabilitation of patients with type 2 diabetes mellitus], KhDAFK, Kharkiv. (in Ukr.)

Kalmykov, S.A. (2008), "Modern approaches to the use of therapeutic physical training in the rehabilitation of patients with type 2 diabetes", Tavriiskyi medyko-biolohichnyi visnyk, T. 11, No.4 (44), pp. 206-210. (in Ukr.)

Kalmykov, S.A. et al. (2008), The method of health gymnastics for patients with type II diabetes. Patent of Ukraine No. 36152. 2008 October 10. (in Ukr.)

Kalmykov, S.A. (2010), "Dislipoproteinemia in type II diabetes mellitus and their correction", Medical perspectives, No. 15(3), pp. 79-84. (in Ukr.)

Kalmykov, S.A. (2010). "Study of the state of physical workability in patients with insulin-dependent diabetes mellitus under the influence of a program of physical rehabilitation", Health-saving technologies, physical rehabilitation and recreation in higher education institutions, No. 3, pp. 82-86. (in Ukr.)

Kalmikov, S. (2012), "Dynamics of indexes of carbohydrate exchange at patients by saccharine diabetes of 2th type on a background application of facilities of physical rehabilitation", Slobozhanskiy herald of science and sport, No. 5-1 (32), pp. 102-105. (in Ukr.)

Kalmykov, S.A., Manucharian, S.V. & Myronova, H.V. (2016), "An analysis of the effectiveness of physical rehabilitation of men of the second mature age with ischemic stroke at the inpatient stage", Fizychna reabilitatsiia ta rekreatsiino-ozdorovchi tekhnolohii, No. 2, pp. 21-23. (in Ukr.)

Kalmykov, S.A. (2010), "Study hemodynamic findings variability, vegetative nervous system state and glycemia level in patiets with diabetes mellitus type II against background of physical rehabilitation means", Medical perspectives, No. 15(4), pp. 46-51. (in Ukr.)

Kalmykov, S.A., Kalmykova, Yu.S. & Poruchchykova, L.G. (2015), "Evaluation of the effectiveness of therapeutic physical education techniques in hypertensio", Problemy bezperervnoi medychnoi nauky ta osvity, No. 1(17), pp. 19-24. (in Russ.)

Kalmykovа, Y.S. (2013). "Features of medical feed at saccharine diabetes", Pedagogics, psychology, medical-biological problems of physical training and sports, No. 17(1), pp. 30-33.

Kalmykova, Yu.S. & Orshchatska, N.V. (2019), "Current views on the use of physical therapy in hypertension", Fizychna reabilitatsiia ta rekreatsiino-ozdorovchi tekhnolohii, No. 3(1), pp. 11-16. (in Ukr.)

Kalmykova, Y., Kalmykov, S., Polkovnyk-Markova, V. & Reutska, A. (2018), "Application and influence of the complex program of physical therapy on the state of the cardiovascular and autonomic nervous system of young women, patients with alimentary obesity", Slobozhanskyi herald of science and sport, No. 5 (67), pp. 22-27. (in Ukr.)

Kalmykova, Yu.S. (2014), Metody doslidzhennya u fizychniy reabilitatsiyi: doslidzhennya fizychnoho rozvytku [Methods of research in physical rehabilitation: research on physical development], KhSAPC, Kharkiv. (in Ukr.).

Kalmykova, Y.S., Kalmykov, S.A. & Sadat, K.N. (2017), "Application of means of physical therapy in restorative treatment of hypertension", Fizychna reabilitatsiia ta rekreatsiino-ozdorovchi tekhnolohii, No. 1, pp. 16-26. (in Ukr.)

Kalmykova, Iu.S. & Yakovenko, L.Iu. (2015), "Osoblyvosti zastosuvannia metodyk likuvalnoi fizychnoi kultury pry hipertonichnii khvorobi I stadii", Physical Culture, Sport and Health: Materials of II All-Ukrainian Student Scientific Internet Conference. KhSAPC, Kharkiv, pp. 195-197. (in Ukr.)

Kalmykov, S. & Kalmykova, J. (2016), "The characteristics of the medicinal plants used in the herbal medicine оf type 2 diabetes", Slobozhanskyi herald of science and sport, No. 3 (53), pp. 26-30.

Kalmykov, S.A. (2007), "Topical issues of therapeutic physical culture in the rehabilitation of patients with type II diabetes mellitus", Slobozhanskiy herald of science and sport, No. 12, pp. 171-174.

Kalmykov, S.A. & Fedi, B.S. (2016), "Topical issues of non-pharmacological therapy of the initial stages of hypertensive disease", Fizychna reabilitatsiia ta rekreatsiino-ozdorovchi tekhnolohii, No. 3, pp. 101-108. (in Russ.)

Kirichenko, M.P., Kalmykov, S.A. & Kalmykova, Yu.S. (2012), "Features of cardiovascular reaction on physical exertion in patients with diabetes mellitus 2nd type under influence of physical rehabilitation means", Experimental and Clinical Medicine, No. 4, pp. 71-73.

Mamedov M.N. (2004), Rukovodstvo po diagnostike i lecheniyu metabolicheskogo sindroma: metodicheskie rekomendatsii [Guidelines for the diagnosis and treatment of metabolic syndrome: guidelines], Meditsina, Moskva, pp. 72-75.

Marchenko, V.O. & Kalmykova, Yu.S. (2017), "Analiz efektivnostі programmy fizichnoi terapії v alimentarnomu obzhirnnі", Fizychna reabilitatsiia ta rekreatsiino-ozdorovchi tekhnolohii, No. 1, pp. 33-43. (in Ukr.)

Masterov, O.S. & Kalmykov, S.A. (2017), "Analiz result in korektsіgi gіperglikemії at tsukrovom dіabetі 2 type zasolami fizichnoy terapії", Fizychna reabilitatsiia ta rekreatsiino-ozdorovchi tekhnolohii, No. 1, pp. 44-52. (in Ukr.)

Mitchenko, O.I. (2004), "Patohenetychni osnovy metabolichnoho syndromu", Nova medytsyna, No. 3, pp. 20-24. (in Ukr.)

Dedov, I.I. (2000), Ozhirenie. Metabolicheskiy sindrom. Sakharnyy diabet 2 tipa [Obesity. Metabolic syndrome. Type 2 diabetes mellitus], Moscow. (in Russ.)

Popov, S.N., Valeev, N.M. & Garaseeva, T.S. (2008), Lechebnaya fizicheskaya kultura [Therapeutic physical culture], Akademiya, Moscow. (in Russ.)

Popov, S.N. (2005), Fizicheskaya reabilitatsiya [Physical rehabilitation], Feniks, Rostov n/D. (in Russ.)

Ratsun, M., Peshkova, O.V. & Kalmykov, S.A. (2015), "Complex physical rehabilitation at hypertension and stage I at the sanatorium stage of rehabilitation", Actual problems of medico-biological support of physical culture, sports and physical rehabilitation: the All Materials I Internship nauk. and practical. Internet Conf., 23 April 2015. KhSAPC, Kharkiv. 127-130. (in Ukr.)

Tronko, M.D. (2015), "Current status and prospects of development of fundamental and clinical endocrinology for 2015-2020", Endokrynolohiia, Vol. 20, No 1. pp. 373-381. (in Ukr.)

Turco, L.V. & Kalmykov, S.A. (2015), "Application of physical rehabilitation facilities for coronary heart disease", Zbirnyk naukovykh prats Kharkivskoi derzhavnoi akademii fizychnoi kultury, No. 2, pp. 219-225. (in Ukr.)

Chazova, I.Ye. & Mychka, V.B. (2015), Profilaktika, diagnostika i lechenie metabolicheskogo sindroma [Prevention, diagnosis and treatment of metabolic syndrome], Moscow. (in Russ.)

Framingham Heart Study. Official site (2020), available at:

The President and Fellows of Harvard College. Official site (2020), available at:

Colditz, G.A., Philpott, S.E. & Hankinson, S.E. (2016), "The Impact of the Nurses’ Health Study on Population Health: Prevention, Translation, and Control", American Journal of Public Health, Vol. 106, No. 9, pp. 1540-1545.

Convention for the protection of Human Rights and Dignity of the Human Being with regard to the Application of Biology and Medicine: Convention on Human Rights and Biomedicine. Council of Europe. Oviedo, 04.04.1997, available at:

Hodis, H N., Kramsch, D.M., Avogaro, P., Bittolo-Bon, G., Cazzolato, G., Hwang, J. & Sevanian, A. (1994), "Biochemical and cytotoxic characteristics of an in vivo circulating oxidized low density lipoprotein (LDL-)", Journal of lipid research, No. 35(4), pp. 669-677.

Kalmykov, S.A., Kalmykova, Y.S. & Bezyazichnaya, O.V. (2015), "Study of variability of antropometric and hemodynamic parameters in patients with alimentary obesity on the background of application of physical rehabilitation technique", News of science and education, No. 15(39), pp. 38-46.

Kalmykova, Y., Kalmykov, S. & Bismak, H. (2018), "Dynamics of anthropometric and hemodynamic indicators on the condition of young women with alimentary obesity in the application of a comprehensive program of physical therapy", Journal of Physical Education and Sport, No. 18(4), pp. 2417-2427, doi:10.7752/jpes.2018.04364.

Kaplan, N.M. (1989), "The deadly quartet: upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension", Archives of internal medicine, No. 149(7), pp. 1514-1520.

Lang, G.F. (1938), Uchebnik vnutrennikh bolezney (Textbook of internal medicine), Vol. 1, P. 1, Biomedgiz, Moscow-Leningrad. (in Russ.)

Lang, G.F., Мирон, С.В., Мясников, А.Л. (1938), Bolezni sistemy krovoobrashcheniya (The diseases of the circulatory system), Medgiz, Leningrad.

Mahmood, S.S., Levy, D., Vasan R.S., Wang, T.J. (2014), "The Framingham heart study and the epidemiology of cardiovascular disease: A historical perspective", Lancet., No. 383, pp. 999-1008.

Reaven, G.M. (1988), "Role of insulin resistance in human disease", Diabetes, No. 37(12), pp. 1595-1607.

Reaven, G.M., Lithell, H. & Landsberg, L. (1996), "Hypertension and associated metabolic abnormalities – the role of insulin resistance and the sympathoadrenal system", New England Journal of Medicine, No. 334(6), pp. 374-382.

Wong, N.D. & Levy, D. (2013), "Legacy of the Framingham heart study: Rationale, design, initial findings, and implications", Glob Heart, No. 8, pp. 3-9.

World Medical Association (2013), "Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects", JAMA, T. 310 (20), pp. 2191-2194, doi:10.1001/jama.2013.281053.

Yuliya, K. & Sergey, K. (2018), "Physical exercise application for the correction of carbohydrate metabolism in diabetes mellitus", Journal of Physical Education and Sport, No. 18(2), pp. 641-647, doi:10.7752/jpes.2018.02094

Kalmykov, S. & Kalmykova, Y. (2017), "Dynamics of cardiovascular parameters in combined aortic malformations under the influence of a physical therapy program during the rehabilitation process", Slobozhanskyi herald of science and sport, No. 6 (62), pp. 43-47.

Graevskaya, N.D. & Dolmatova, T.I. (2004), Sportivnaya meditsina [Sports medicine], Sovetskiy sport, Moscow. (in Russ.)

Makarova, G.A. (2003), Sportivnaya meditsina [Sports medicine], Sovetskiy sport, Moscow. (in Russ.)

Nishimura, R.A., Otto, C.M., Bonow, R.O. et al. (2017), "2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines", Circulation, Vol. 135, pp. e1159-e1195.

Ministry of Health of Ukraine (2013), "Methodical recommendations on counseling patients on the basic principles of healthy eating (in accordance with the order No. 16 of 14.01.2013)", International Endocrinology Journal, No. 5 (53), pp. 138-147.

Kalmykov, S.A. (2008), Fіtoterapіya [Phytotherapy], KhSAPC, Kharkiv. (in Ukr.)