Assessment of the role of ultrasound diagnostic methods in identifying PIN

Authors

  • M.P. Melnychuk State institution of science “Research and practical center of preventive and clinical medicine” State administrative department, Ukraine
  • O.O. Lulko Zaporizhzhya regional clinical hospital, Ukraine
  • A.Z. Zhuravchak State institution of science “Research and practical center of preventive and clinical medicine” State administrative department, Ukraine

DOI:

https://doi.org/10.26641/2307-5279.22.4.2018.152486

Keywords:

prostate intraepithelial neoplasia, ultrasound investigation, dopplerography

Abstract

The article is dedicated to the problem of prostate intraepithelial neoplasia ultrasound diagnostics. The objective was to determine specific ultrasound features of PIN. Transrectal ultrasound and Doppler data of 166 patients with high grade and low grade PIN were analysed. Such ultrasound features as echogenicity (hypo-, iso- and hyperechogenic) and vascularisation grade (hypo-, iso- and hypervascularisation) of prostate samples with PIN were compared. There was no any statistically confirmed difference in echogenicity and vascularisation determined between high and low grade PIN and normal prostate tissue. Investigation data indicate low significance of transrectal ultrasound and dopplerography in diagnostics of prostate intraepithelial neoplasia.

References

World Health Organization. Health Statistics and Information Systems: WHO Mortality Database. URL: http://who.int/healthinfo/mortality_data/en/. Accessed November 6, 2014.

De Nunzio C., Albissini S., Cicione A., Gacci M. Widespread High-grade Prostatic Intraepithelial Neoplasia on biopsy predicts the Risk of Prostate Cancer // Archivio Italiano di Urologia e Andrologia. – 2013. – Vol. 85, N 2. – P. 59–64.

Haffner M., Barbieri C. Shifting paradigms for high-grade prostatic intraepithelial neoplasia //European Urology. – 2016. – Vol. 69, N 5. – P. 831–833.

Taneja S., Morton R. Prostate cancer diagnosis among men with isolated high-grade intraepithelial neoplasia enrolled onto a 3-year prospective phase III clinical trial of oral toremifene // J. Clin. Oncol. – 2013. – Vol. 31. – P. 523–529.

Tao Z., Shi A. Epidemiology of prostate cancer: current status // European review for Medical and Pharmakological Sciences. – 2015. – Vol. 19. – P. 805–812.

Patel P., Nayak Y., Biljetina Z., Donnelly B. Prostate cancer after initial PIN and benign prostate biopsy // The Canadian Journal of Urology. – 2015. – Vol. 22. – P. 8056–8062.

Munireddy M., Girish H., Prasad K., Rajareddy H. Prevalence of Prostatic Intraepithelial Neoplasia in Patients Diagnosed as Benign Prostatic Hyperplasia Underwent Transurethral Resection // International Journal for Scientific Study. – 2016. – Vol. 3. – P. 134–138.

Lopes P., Sepulveda L., Ramos R., Sousa P. The role of transrectal ultrasound in the diagnosis of prostate cancer: new contributions // Radiol Bras. – 2015. – Vol. 48. – P. 7–11.

Marks L., Young S. MRI-ultrasound fusion for guidance of targeted prostate biopsy // Curr Opin Urol. – 2013.

Downloads

Published

2018-12-23

Issue

Vol. 22 No. 4 (2018)

Section

Oncourology

License

Стаття повинна мати візу керівника та офіційне направлення від установи, з якої виходить стаття (з круглою печаткою), і вказівкою, чи є стаття дисертаційною, а також у довільній формі на окремому аркуші - відомості про авторів (прізвище, ім’я, по батькові, посада, вчений ступінь, місце роботи, адреса, контактні телефони, E-mail).

Стаття повина бути підписана всіма авторами, які укладають з редакцією договір пропередачу авторських прав (заповнюється на кожного автора окремо з оригінальним підписом). За таких умов редакція має право на її публікацію та розміщення на сайті видавництва.