BIOTECHNICAL SYSTEM FOR INTEGRATED OLFACTOMETRY DIAGNOSTICS

Authors

DOI:

https://doi.org/10.30837/2522-9818.2017.1.064

Keywords:

olfactory test, odorivector, rhinomanometer, olfactometry, energy characteristic

Abstract

The subject matter of the article is the process of olfactometric research of a human olfactory function. The object of the study is a biotechnical system which includes a method for increasing the objectivity of olfactometric diagnostics. The goal is to develop a biotechnical system for complex olfactometry, which enables increasing the objectivity of olfactometric studies and connecting breathing parameters with olfactory function by placing an odorant carrier in the airway of the rhinomanometer, as well as by using procedures for determining the energy characteristics of respiration. The methods used are: methods of digital signal processing, the theory of biotechnical systems. The following results are obtained. A structural diagram of a biotechnical system for olfactometric diagnostics of a human olfactory analyser was developed. As a result of the analysis of the cyclogram of nasal breathing, it is found that by changing the frequency and nature of breathing upon reaching the sensitivity threshold, it is possible to objectify the method of assessing respiratory and olfactory disorders according to the energy criterion of pneumatic power when inhaling appropriate odorivectors, and also to study the olfactory and respiratory function with the capability of estimating respiratory cycles in a dynamic mode. The studies were carried out on the basis of typical inspiration cycles: with a quiet breathing in the normal conditions, in the forceful breathing mode with a stiff nasal valve, with a nasal valve with natural functional mobility which restricts the flow of air, and also a stepped inspiration – a short “sipping” of air, which can be characterized as a kind of “sniffing”. Conclusions. Computer olfactometry is one of the most promising methods for diagnosing olfactory disorders of respiratory genesis. The developed biotechnical system is based on the use of a fundamentally new design, combining a rhinomanometer and an olfactometric nozzle with a container for an odorant. A feature of this system is also the capability to determine the energy characteristics of nasal breathing when the sensitivity threshold of the odorivector is reached. The future direction of the work is to specify the concentrations of odorants for the biotechnical system for olfactometric diagnostics, which enables testing the sensitivity of the olfactory analyser on outpatient basis.

Author Biographies

Yana Nosova, Kharkiv National University of Radioelectronics

post-graduate student at the Department of Biomedical Engineering

Oleg Avrunin, Kharkiv National University of Radioelectronics

Chief of the Department of Biomedical Engineering

Valery Semenets, Kharkiv National University of Radioelectronics

Rector

References

Alekseeva, N., Ponomareva, T. (2014), "Diagnosis of olfactory impairment with the help of the Snuffin Styx test for Parkinson's disease and polypous rhinosinusitis", Bulletin of Otorhinolaryngology, No. 1, pp. 37-40.

Avrunin, О., Shushlyapina, N., Nosova, Y., Bogdan, О. (2016), "Olfactometry diagnostic at the modern stage", Bulletin of NTU "KhPI". Series: New solutions in modern technologies, NTU "KhPI", Kharkiv, No. 12 (1184), pp. 95-100, DOI: 10.20998/2413- 4295.2016.12.13

Kim, W. S., Jang, D. P., Kim, In Y. (2014), "The Current Status of Evaluation Technologies for the Function of Human Olfaction", Hanyang Med Rev, No. 34, pp. 120-124.

Heiselmann, H. L., Rivlin, R. S. (1986), "Clinical measurement of taste and smell", New York, pp.170-186.

Dzaman, K., Rapiejko, P., Szczygielski, K. et al. (2009), "Taste perception in patients with chronic rhinosinusitis with nasal polyps treated with oral glucocorticosteroid therapy", Otolaryngol, Vol. 63, No. 3, pp. 236-241.

Vodichka, J., Pellant, A., Chrobok, V. (2007), "Screening of olfactory function using odorized marcers", Rhinology, Vol. 44, pp. 164-168.

Zhao, H., Wei, Y., Miao, X. (2007), "Correlation between olfactory disoders and morphology of nasal cavity", Lin. Chung. Er. Bi. Yan., Vol. 21, pp. 771-774.

Ciprandi, G., Mora, F., Cassano, M. (2009), "Visual analog scale (VAS) and nasal obstruction in persistent allergic rhinitis", Otolaryngol. Head Neck Surg, Vol. 141, pp. 527-529.

Scadding, G., Hellings, P., Alobid, I., Bachert, C., Fokkens, W. et al. (2011), "Diagnostic tools in Rhinology EAACI position paper", Clinical and Translational Allergy, No. 1:2, pp. 1-39.

AyaFukasawa, K. O. (2013), "Olfactory Measurement Method at Health checkup with Olfactory Display using Pulse Ejection", International Journal of Informatics Society, No. 5, pp. 13-19.

Doty, R. L. (2012), "Olfactory dysfunction in Parkinson disease”, Nat. Rev. Neurol, Vol. 8., pp. 329-339.

Stalemate. No. 91762 Ukraine, IPC A61B 5/08. Device for testing nasal breathing / Avrunin O., Zhuravlev A., Kalashnik M., Yaschenko M., Semenets V.; Applicant and patent holder Kharkiv National University of Radio Electronics. No. а200814356; applied. 15.12.2008; publ. 25.08.2010, Bul.;. No. 16.

Avrunin, O. (2011), "Principles of Computer Planning of Functional Operational Interventions", Technical Electrodynamics, Issue "Power Electronics and Energy Efficiency", Vol. 2, pp. 293-298.

Device for testing respiratory disturbances of olfactory: pat. 110452 С2 Ukraine: МПКА61В 5/08 (2006.01) / Avrunin O., Zhuravlev A., Shushlyapina N., Nosova Y., Faruk Kh., Applicant and Patent Owner Kharkiv National University of Radio Electronics. No. 201500603; stated. January 26, 2015; published Jun 10, 2015, Bul. No. 11, 4 p.

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How to Cite

Nosova, Y., Avrunin, O., & Semenets, V. (2017). BIOTECHNICAL SYSTEM FOR INTEGRATED OLFACTOMETRY DIAGNOSTICS. INNOVATIVE TECHNOLOGIES AND SCIENTIFIC SOLUTIONS FOR INDUSTRIES, (1 (1), 64–68. https://doi.org/10.30837/2522-9818.2017.1.064

Issue

No. 1 (1) (2017)

Section

Technical Sciences

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Copyright (c) 2018 Yana Nosova, Oleg Avrunin, Valery Semenets

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