Design of experiment in the synthesis optimization of vancomycin-selective "artificial receptors"

Authors

  • Екатерина Николаевна Музыка Kharkiv National University of RadioElectronics Lenin Ave. 14, Kharkiv, Ukraine, 61166, Ukraine

DOI:

https://doi.org/10.15587/2313-8416.2014.27623

Keywords:

molecularly imprinted polymer, artificial receptors, vancomicine, affinity, design of experiment

Abstract

The work is focused on the use of chemometric approach to "design of experiment", implemented using MODDE 9.0 software package to optimize the synthesis of the vancomycin-selective nanoparticles ("artificial receptor" based on molecularly imprinted polymers) in an automatic reactor in order to obtain its maximum quantitative yield.

Author Biography

Екатерина Николаевна Музыка, Kharkiv National University of RadioElectronics Lenin Ave. 14, Kharkiv, Ukraine, 61166

PhD, senior researcher

Chair of Biomedical Engineering

References

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6. Muzyka, K., Karim, K., Guerreiro, A., Poma A., Piletsky, S. (2014). Optimisation of the synthesis of vancomycin-selective molecularly imprinted polymer nanoparticles using automatic photoreator. Nanoscale Research Letters, 9 (1), 154–161. http://dx.doi.org/10.1186/1556-276x-9-154

Published

2014-10-14

Issue

Section

Technical Sciences