About a mechanism of the influence of shear stress for viscosity of the blood in vessels of small diameter
DOI:
https://doi.org/10.15587/2313-8416.2014.35085Keywords:
sigma-effect, viscosity, erythrocytes, deformability, water pores, shear stressAbstract
It is proposed a physiological and experimentally confirmed explanation of Fåhraeus-Lindqvist-effect in capillaries using the profile analyses of osmotic deformability of red blood cells. It was shown the dose-dependent change of the erythrocytes deformability in the stage of isotropic spheres after forming artificial water pores (nystatin) and occlusion (PbCl2) of available pores. The Sigma-effect reducing of hematocrit and viscosity in a shear flow of blood through the vessels of a small diameter was conditioned by the interchange of liquid phase between the erythrocyte and the plasma.
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