The state of target-organ damage in pregnant women with different forms of hypertension

Authors

  • Василий Сергеевич Чулков South Ural State Medical University Vorovsky str., 64, Chelyabinsk, Russia, 454092, Russian Federation

DOI:

https://doi.org/10.15587/2313-8416.2015.36015

Keywords:

arterial hypertension, pregnancy, left ventricular hypertrophy, microalbuminuria, the thickness of the intima-media complex

Abstract

We have estimated the state of target-organ damage in 95 pregnant women with different forms of hypertension. The early and potentially reversible pathophysiological and pathomorphological changes of the target organs in pregnant women with hypertension are structural and functional changes of the heart and kidneys. To assess the state of the target organs we were examined the blood vessels of the ocular fundus, the presence of left ventricular hypertrophy, the thickness of the intima-media complex and the presence of microalbuminuria. It was shown that the earliest target-organ damage in pregnant women with hypertension was left ventricular hypertrophy regardless of its form. Detection of microalbuminuria depending on gestational age may serve as an additional criterion of pre-eclampsia. With consideration of the high frequency changes in the retinal vessels, especially in preeclampsia superimposed on chronic hypertension, is required further researches to evaluate the prognostic significance of these changes. Assessment of target organs in pregnant women with hypertension can be used as a surrogate prediction point of complications and adverse pregnancy outcomes.

Author Biography

Василий Сергеевич Чулков, South Ural State Medical University Vorovsky str., 64, Chelyabinsk, Russia, 454092

PhD, associate professor

Faculty Therapy Department

References

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Published

2015-01-27

Issue

Section

Medical