Cytokine status of patients with acute sluggish odontogenic osteomyelitis of the jaw
DOI:
https://doi.org/10.15587/2313-8416.2015.36524Keywords:
immunological status, acute odontogenic osteomyelitis of the jaws, interleukinsAbstract
The content of IL-1β in the serum level was 1,823±0,300 (p<0.001), which is approximately 14.7 times the value of this indicator in healthy individuals - control group (0,124±0,026). The concentration of TNFα in the blood of healthy individuals was 0,196±0,023, while in patients with acute odontogenic osteomyelitis occurs without acute clinical symptoms, observed an increase in the corresponding rate to 2,752±0,624 (p<0.001), almost 14 times. In the study group, it was also a sevenfold increase in the synthesis of IL-6 (22,224±8,244; p<0.001) compared with the control group (3,158±0,214).
The content of anti-inflammatory factors, immunological protection of organism (IL-4) in patients with odontogenic osteomyelitis at admission was 0,462±0,064, which was a statistically significant increase (p>0,05) compared with those in the control group – 0,416±0,058
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