The problem of radiogenic thyroid cancer
DOI:
https://doi.org/10.15587/2313-8416.2015.37682Keywords:
ionizing radiation, Chernobyl accident, genetic instability, thyroid, radiogenic cancerAbstract
Aim. Analysis and compilation of radiation-epidemiological and radiobiological researches showing that exposure is the cause of radiogenic thyroid cancer.
Methods. Radiation-epidemiological, cytogenetic, experimental.
Results. Data analysis of numerous investigations confirms that the thyroid gland belongs to the group of high risk of cancer developing of radiation genesis. The significant differences in the quantitative risk assessment of thyroid cancer of radiation genesis in different populations, irradiated by the Chernobyl accident, are revealed. Iodine deficiency is considered as an effective promoter of radiation carcinogenesis. Attention is focused on the fact that environmental pollution, combined with the increased sensitivity of the epithelium of the thyroid gland to radiation can serve as the basis for a continuing trend towards a higher incidence thyroid cancer in the future.
Conclusions. Analysis and compilation of epidemiological and radiobiological investigations clearly indicate that ionizing radiation is the causative factor in the production of radiogenic thyroid cancer. The current radioecological situation in Ukraine necessitate the need to develop and implement effective strategies for primary prevention of radiogenic cancer at the individual level
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