The impact of neurometabolic therapy on quality of life in patients with consequences of traumatic brain injuries

Authors

  • Юлия Валентиновна Якубенко Kharkiv Medical Academy of Postgraduate Education 58 Korchagintsev st, Kharkiv, Ukraine, 61000, Ukraine

DOI:

https://doi.org/10.15587/2313-8416.2015.42970

Keywords:

consequences of mild traumatic brain injury, quality of life, metabolic therapy

Abstract

The aim of the research was to determine the quality of life of patients with consequences of mild traumatic brain injuries for the effectiveness estimation of the neurometabolic therapy.

Materials and methods. 67 patients with consequences of mild traumatic brain injuries were examined. Patients were divided into two groups: the first group (23 males and 10 females) included patients who received symptomatic therapy. The second group included patients (24 males and 10 females) who received symptomatic therapy and an additional course of neurometabolic therapy. The control group included 30 practically healthy individuals without TBI, corresponding to the examined group by sex and age.

Results. Integral assessment of QoL by the SF-36 health survey scales showed a significant reduction in quality of life by the scales of pain intensity, life activity, social functioning, emotional functioning and mental health. Application of the treatment course of neurometabolic therapy for patients with consequences of mild traumatic brain injury promotes the normalization of neuropsychological disorders in these patients, which has a positive effect on the subjective assessment of quality of life.

Conclusion. Conducting neurometabolic treatment for patients with consequences of mild traumatic brain injury is more effective in comparison with the basic symptomatic treatment, with regard to its impact on the metabolism of the brain, reduction of its susceptibility to chronic hypoxia that develops against the backdrop of vegetative dystonia, caused by an injury. Application of neurometabolic treatment for patients with consequences of traumatic brain injuries leads to the improvement of their quality of life

Author Biography

Юлия Валентиновна Якубенко, Kharkiv Medical Academy of Postgraduate Education 58 Korchagintsev st, Kharkiv, Ukraine, 61000

Postgraduate student

Department of Neurology and the Child Neurology

References

Konovalova, A. N., Likhterman, L. B., Potapov, A. A. (2002). Clinical guidelines for traumatic brain injury. Moscow: Antidoron, 631–638.

Belova, A. N., Shepetova, O. N. (2002). Clinical guidelines for physicians and researchers. Scale tests and questionnaires in medical rehabilitation. Moscow: Antidoron, 71–92.

Brattons, A., Bullock, R. et. al. (2007). Guidelines for the managerment and prognosis of Severe Head Injury. (3d edition) Brain Trauma Foundation, USA. Neurotrauma, 24, 1–100.

Karakulova, U. Y., Selyanina, N. V., Eroshina, O. A. (2011). Quality of life in patients with acute traumatic brain injury under the influence of neurotrophic therapy. Bulletin Siberia meditsiny, 2, 55–78.

Likhterman, L. B. (2009). The clinical benefit for neurosurgeons, neurologists, trauma. Neurology traumatic brain injury. Moscow, 386–392.

Novik, A. A., Ionova, T. I. (2002). Clinical guidelines for the study of the quality of life in medicine. Moscow: Olma-Press Star peaceful, 320–335.

Novik, A. A., Ionova, I. A. (2006). Quality of life research in clinical medicine. Vestn. NMHTS, 1, 91–99.

Karakulova, U. Y., Selyanina, N. V., Eroshina, O. A. (2011). Quality of life in patients with acute traumatic brain injury under the influence of neurotrophic therapy. Bulletin Siberia meditsiny, 2, 55–78.

Andreeva, O. N. (2012). The level and quality of life: the content of the concepts and their components. Ojkumena. Regional studies research, 4, 68–77.

Truelle, J.-L., Koskinen, S., Hawthorne, G., Sarajuuri, J., Formisano, R., Von Wild, K. et. al. The Qolibri Task Force. (2010). Quality of life after traumatic brain injury: The clinical use of the QOLIBRI, a novel disease-specific instrument. Brain Injury, 24 (11), 1272–1291. doi: 10.3109/02699052.2010.506865

Von Steinbüchel, N., Wilson, L., Gibbons, H., Hawthorne, G., Höfer, S., Schmidt, S. et. al. (2010). Quality of Life after Brain Injury (QOLIBRI): Scale Development and Metric Properties. Journal of Neurotrauma, 27 (7), 1167–1185. doi: 10.1089/neu.2009.1076

Nichol, A. D., Higgins, A. M., Gabbe, B. J., Murray, L. J., Cooper, D. J., Cameron, P. A. (2011). Measuring functional and quality of life outcomes following major head injury: Common scales and checklists. Injury, 42 (3), 281–287. doi: 10.1016/j.injury.2010.11.047

Published

2015-05-28

Issue

Section

Medical