The features of endometrium receptor apparatus in women with missed abortion
DOI:
https://doi.org/10.15587/2313-8416.2015.43093Keywords:
missed abortion, endometrium receptor apparatus, endometrial proteinAbstract
A new complex of modern methods of investigation, both the endometrium and immune system changes in local and hormonal status is developed in this article, rehabilitation of reproductive function in patients with the missed abortion is proposed.
Methods. The study involved 124 women, including 64 women with diagnosed missed abortion. The comparison group included 30 women with physiological pregnancy who were performed artificial abortion. 30 healthy women in pregravidae period were examined. The clinical and anamnestic, histological and immunological features of the endometrium and its functional activity were investigated.
Results. Pathogenetic mechanisms of menstrual dysfunction were defined in women with the missed abortion. The changes in the secretory transformation of the endometrium, a sharp decrease in its receptor and functional activity, confirming the lack of development of the luteal phase are observed. Based on the research, an algorithm for the restoration of menstrual function in women in the postgravidae period is developed and implemented in practice.
Conclusions. The data confirmed the feasibility of implementing the proposed examination and treatment of women with the missed abortion
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Copyright (c) 2015 Александра Николаевна Тищенко, Ольга Валентиновна Юркова, Виктория Валентиновна Лазуренко
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