Features of course of endotoxemia and "metabolic" intoxication in athletes depending on the degree of exercise stress
DOI:
https://doi.org/10.15587/2313-8416.2015.43298Keywords:
sports, immunity, athletics, endotoxemia, exercise stress, athletesAbstract
Modern sports more often associated with the occurrence of immunodeficiency - a reduction in the functional activity of the main components of the immune system. This leads to disturbances in the system of antibiotic resistance of the organism and the growth of infectious diseases of athletes.
Therefore, the aim of the study was to explore the features of endotoxemia and "metabolic" intoxication in athletes depending on the exercise stress. 43 athletes were examined during long-term training.
Results. On the basis of the study we found that endotoxemia course of light and medium degree to proportional stress levels is determined in the first and second group. The endotoxemia course is associated with a decrease in the toxin-associated ability of serum albumin, which is a measure of cytolytic activity of albumin fractions and accumulation of toxins of medium size (10-200 nm) of microbial origin and hydrophobic nature in plasma of peripheral blood. Calculation methods for determining the severity of endotoxemia can be used to identify different mechanisms of its formation and give the opportunity to some extent, reflect the complex toxicometry parameters of athletes to determine the levels of adaptive reactions in response to exercise stress
References
Aronov, G. E., Ivanova, N. I., Aronov, G. E., Kozlov, M. I. (1986). Effect of physical activity of varying intensity on the state of immunological reactivity. J. Immunology and Allergology, 20, 76–79.
Vysochin, Y., Denisenko, Y. P. (2002). Modern understanding of the physiological mechanisms of urgent adaptation of sportsmen to the effects of physical activity. J.Theory and Practice fizkultury, 7, 2–6.
Kodrashov, G. F., Rozov, E. A. (1971). Status of certain factors of natural immunity in athletes during competitions. Tallinn, 32.
Liapin, V., Andreeva, V., Nikolaychuk, N. (2009). Influence of seasons on the state of immunity wrestlers. J.Fіzichne vihovannya sport i Zdorov'ya culture in Suchasnyj suspіlstvі, 3, 106–109.
Lіapin, V. P., Badalich, N. G., Shelyakina, E. A., Korotun, V. A. (1993). Change mechanism of the immune system in athletes during training process. J. Ecology of the industrial region of Donbass. Lugansk, 102–105.
Suzdalnitsky, R. S., Levando, V. A. (1998). Immunological aspects of sports activities man. J.Theory and Practice nat. culture, 10, 43–46.
Suzdalnitsky, R. S., Levando, V. A. (2003). New approaches to the understanding of sports stress immunodeficiencies. J.Theory and Practice nat. culture, 1, 18–22.
Tajmazov, V. A., Tsygan, V. N., Mokeeva, E. G. (2003). Sports and immunity. St. Petersburg, 200.
Khaitov, R. M. Pinegin, B. V., Istamov, H. I. (1995). Environmental Immunology. Moskov, 219.
Dobronravov, A. B., Tikhvinski, B., Khrushchev, S. V. (1991). Influence of systematic sports on the blood system of young sportsmen. J. Children's Sports Medicine, 158–168.
Zdrodovsky, P. F., Golinevich, E. M. (1972). Doctrine of Ricketts and rikketsiozah. Moscow, 494.
Pedersen, B. K. (2000). Exercise and cytokines. Immunology and Cell Biology, 78 (5), 532–535. doi: 10.1111/j.1440-1711.2000.t01-11-.x
Sorokinа, O., Kozynets, G. P. (2009). Nutritional support for patients in critical condition J. Scientific-methodical Manual, 163.
Suzdalnitsky, R. S. Levando, V. A., Kassil, G. N. (1990). Stress and immune deficiencies in humans sports. J.Theory and Practice fiz..kultury, 6, 9–17.
Suzdalnitsky, R. S., Levando, V. A., Pertin, B. A. (1989). Temporary immunodifetsit caused by excessive exercise. J.Theory. And Scient. P. kultury, 2, 14–16.
Nazar, P. S., Osadcha, O. I., Shevchenko, O. O., Shmatova, O. O. (2012). Dynamics of lymphocytes and cellular immunity indexes athletes stayer in front adversarial and competitive periods. J. Olympic sport Physical culture, health nation in sovremennыh conditions, 256–260.
Nazar, P. S., Shevchenko, O. O., Osadcha, O. I., Levon, M. M. (2013). Dynamics of pro- and anti-inflammatory cytokines in athletes stayer in various physical activities. J. Olympic sport Physical culture, health nation in modern conditions, 58–62.
Nazar, P. S., Shevchenko, O. A. (2013). Applied Immunology. Kyiv, 626.
Anokhin, P. K. (1975). Essays on the physiology of functional system. Moskov, 477.
Pasteur, E. W. (1989). Immunology workshop. Kiev, 304.
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Copyright (c) 2015 Марія Михайлівна Левон, Олена Олександрівна Шевченко, Павло Степанович Назар, Яна Вікторівна Зіневич, Оксана Іванівна Осадча
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