Echocardiographic changes in women with chronic heart failure depending on the body mass index
DOI:
https://doi.org/10.15587/2313-8416.2015.51545Keywords:
echocardiographic changes, women, chronic heart failure, body weight indexAbstract
Chronic heart failure (CHF) is a widespread disease of cardiovascular system its prevalence is caused with improvement of diagnostic methods simultaneously with an aging of general population. Women are the half of all patients with CHF most of them has preserved fraction of output from the left ventricle with associated diastolic dysfunction. The aim of research was the study of echocardiographic changes in women with chronic heart failure depending on body weight index.
Methods: There were examined 237 women with different body weight index (BWI), in 222 was diagnosed CHF of 1-111 functional class (FC). All patients underwent calculation of BWI using Ketle formula and Doppler-echocardiographic examination. The calculations of results were carried out using the methods of parametric and nonparametric statistics depending on size and distribution of samples.
Results: In women with CHF the growth of dilatation of aorta, right atrium and left ventricle take place at an increase of BWI. The maximal size of the left atrium and right ventricle were registered in the group of examined person with normal body weight. The hypertrophy of left ventricle myocardium in women with CHF progresses proportionally to an increase of BWI. In patients with CHF on the background of obesity the deeper processes of valvular calcination take place. There were not observed the reliable differences between the main groups in the prevalence of systolic dysfunction but there takes place a tendency to its predominance in examined persons with normal body weight. In women with CHF with an increase of BWI takes place the deepening of diastolic dysfunction (by the type of relaxation disorder) and an increase of its prevalence. The remodeling of myocardium in women with CHF in most cases was presented by concentric hypertrophy of the left ventricle and its frequency is directly proportional to an increase of BWI.
Conclusions: There were established that with an increase of BWI in women with CHF the dilatation of aorta, left ventricle and right atrium, hypertrophy of myocardium and valvular calcification are more intense. There was observed a tendency to predominance of the systolic dysfunction in women with CHF and normal body weight. The prevalence and heaviness of diastolic dysfunction by the type of relaxation disorder of the left ventricle grows up proportionally to an increase of BWI. Remodeling of myocardium in most cases is represented by concentric hypertrophy of LV and its frequency rises with an increase of BWI
References
D’Agostini, G., Cicoira, M., Vassanelli, C. (2013). Heart failure in women: a disease with peculiar pathophysiological mechanisms and clinical presentation. American Journal of Cardiovascular Disease Research, 1 (1), 1–6.
O’Meara, E., Clayton, T., McEntegart, M. B., McMurray, J. J. V., Pina, I. L., Granger, C. B. et. al (2007). Sex Differences in Clinical Characteristics and Prognosis in a Broad Spectrum of Patients With Heart Failure: Results of the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM) Program. Circulation, 115 (24), 3111–3120. doi: 10.1161/circulationaha.106.673442
Martínez-Sellés, M., Doughty, R. N., Poppe, K., Whalley, G. A., Earle, N., Tribouilloy, C. et. al (2012). Gender and survival in patients with heart failure: interactions with diabetes and aetiology. Results from the MAGGIC individual patient meta-analysis. European Journal of Heart Failure, 14 (5), 473–479. doi: 10.1093/eurjhf/hfs026
Jong, P., Vowinckel, E., Liu, P. P., Gong, Y., Tu, J. V. (2002). Prognosis and Determinants of Survival in Patients Newly Hospitalized for Heart Failure. Archives of Internal Medicine, 162 (15), 1689. doi: 10.1001/archinte.162.15.1689
Hsich, E. M., Piña, I. L. (2009). Heart Failure in Women. Journal of the American College of Cardiology, 54 (6), 491–498. doi: 10.1016/j.jacc.2009.02.066
Shafazand, M., Schaufelberger, M., Lappas, G., Swedberg, K., Rosengren, A. (2008). Survival trends in men and women with heart failure of ischaemic and non-ischaemic origin: data for the period 1987-2003 from the Swedish Hospital Discharge Registry. European Heart Journal, 30 (6), 671–678. doi: 10.1093/eurheartj/ehn541
Kravchun, P. P. (2015). Genderni ta vikovi osoblyvosti remodeljuvannja sercja u hvoryh iz postinfarktnym kardiosklerozom, cukrovym diabetom 2-go typu ta ozhyrinnjam. Mezhdunarodnyj endokrynologycheskyj zhurnal, 2 (66), 20–24. Available at: http://www.mif-ua.com/archive/article/40542
Hubert, H. B., Feinleib, M., McNamara, P. M., Castelli, W. P. (1983). Obesity as an independent risk factor for cardiovascular disease: a 26- year follow-up of participants in the Framingham Heart Study. Circulation, 67 (5), 968–977. doi: 10.1161/01.cir.67.5.968
Kravchun, P. P. (2014). Zminy diastolichnoi' funkcii' miokarda livogo shlunochka u hvoryh iz postinfarktnym kardiosklerozom ta arterial'noju gipertenzijeju zalezhno vid stupenja ozhyrinnja. Medycyna neotlozhnыh sostojanyj, 6 (61), 158–160. Available at: http://www.mif-ua.com/archive/article/39435
Voronkov, L. H. et. al (2013). Rekomndacii po diahnostike I lecheniu khronicheskoi serdechnoi nedostatochnosti (2012) [Guidelines for the diagnosis and treatment of chronic heart failure (2012)]. Ukrainian cardiology journal, 1, 6–44.
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