Influence of beta-adrenoblockers on structural-functional heart indices in patients with acute q-wave myocardial infarction
DOI:
https://doi.org/10.15587/2313-8416.2015.53930Keywords:
myocardium infraction, heart aneurism, heart rhythm variability, daily profile of arterial pressure, postinfraction remodelingAbstract
The problem of myocardium infraction (MI) remains actually. An early postinfraction period is characterized with intensive remodeling of the left ventricle (LV) and high risk of dangerous complications that is ten times more than the monthly number of complications during the next year. The aim of research was the study of an influence of beta-1 adrenoreceptors on the heart rhythm variability, ectopic heart activity, daily profile of arterial pressure, postinfraction remodeling in patients with an acute Q-myocardium infraction.
Methods. There were examined 235 patients with Q-myocardium infraction. There was evaluated the risk of forming LV aneurism, dynamic indices of combined daily monitoring of arterial pressure and electrocardiogram, echocardiography under influence of the complex treatment using beta-1 adrenoreceptors blockers.
Results. Under an influence of treatment there was established the growth of temporal indices of the heart rhythm variability (HRV), spectral indices that present the parasympathetic influence on the background of decrease of the spectral components of sympathetic origin and mean HR, decrease of ectopic heart activity, normalization of daily profile of arterial pressure, improvement of systolic and diastolic function of LV.
Conclusions. The use of beta-1 adrenoreceptors in the complex treatment of patients with acute Q-MI decreases the risk of forming LV aneurism, favors an improvement of HRV indices, ectopic heart activity, daily profile of arterial pressure, intracardiac hemodynamics
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