Functional state of palatine tonsils in children with diabetes type 1

Authors

  • Андрей Афанасиевич Лайко Shupyk National Medical Academy of Post-Graduate Education 9 Dorogozhitska str., Kyiv, Ukraine, 04112, Ukraine
  • Юрий Владимирович Гавриленко Shupyk National Medical Academy of Post-Graduate Education 9 Dorogozhitska str., Kyiv, Ukraine, 04112, Ukraine
  • Ирина Евгеньевна Волгина Ukrainian Reference Centre for Clinical Laboratory Diagnostics and Metrology of the National Children Specialized Hospital “Ohmatdet” of Ministry of Public Health of Ukraine 28/1 Chornovil str., Kyiv, Ukraine, 01135, Ukraine

DOI:

https://doi.org/10.15587/2313-8416.2016.59330

Keywords:

chronic tonsillitis, palatine tonsils, cytology, diabetes mellitus type 1, children

Abstract

Actuality. Chronic disease of lymphoepithelial throat structures (CHLTS) in children with diabetes mellitus type 1 (DM-1) are widespread according to our earlier studies. The frequent exacerbations lead to the rise of glycemia profile, worsening of patient life quality and effectiveness of the complex therapy of the main disease.

Aim of research: to assess the functional state of palatine tonsils in children and teenagers with DM-1 and chronic tonsillitis.

Materials and methods. During the period 2014-2015 years there was carried out clinical and laboratory examination of 51 children with DM-1 6-18 years old. All children were treated in endocrinological department of National child specialized hospital “Ohmatdit”. The main group of observance included 40 children with DM-1 and CT, the control one included 11 children and teenagers with DM-1 without ENT-pathology. All children of the main and control groups underwent cytological examination of the tonsillar crypt lacunas content.

Results and discussion. The highest specific weight of the chronic diseases of lymphepithelial throat structures (CDLTS) in the main group of observation was revealed at the presence of chronic tonsillitis. In children with DM-1was diagnosed CT – 17 (33,3 %), CT and nasal septum curvature– 16 (31,3 %), CT and adenoid – 9 (17,7 %), CT and palatine tonsils hypertrophy – 5 (9,8 %), CT and recidivous nasal bleedings – 4 (7,8 %). According to the results of this examination in children with CDLTS and DM-1 were separated the four cytological groups that characterize the functional state of palatine tonsils.

I. Good functional power of palatine tonsils.

II. High activity of lymphoid tissue of palatine tonsils.

III. Compensated functional power of palatine tonsils.

IV. Decompensation of palatine tonsils functions.

Conclusion. Cytological examination of tonsillar crypt lacunas content in children and teenagers with DM-1 may be the accessible and informative method of assessment of the functional activity of palatine tonsils, for more precise diagnostics of CT in patients with DM-1, the detection of its form, an effectiveness of the treatment

Author Biographies

Андрей Афанасиевич Лайко, Shupyk National Medical Academy of Post-Graduate Education 9 Dorogozhitska str., Kyiv, Ukraine, 04112

M.D., Profesor

Department of pediatric otorhynolaryngology, audiology, phoniatry

Юрий Владимирович Гавриленко, Shupyk National Medical Academy of Post-Graduate Education 9 Dorogozhitska str., Kyiv, Ukraine, 04112

Candidate of Medical Sciences

Department of pediatric otorhynolaryngology, audiology, phoniatry

Ирина Евгеньевна Волгина, Ukrainian Reference Centre for Clinical Laboratory Diagnostics and Metrology of the National Children Specialized Hospital “Ohmatdet” of Ministry of Public Health of Ukraine 28/1 Chornovil str., Kyiv, Ukraine, 01135

Laboratory doctor of the highest category, the head of the Common Clinical Research Department

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Published

2016-01-30

Issue

Section

Medical