On the question of improving the efficiency and safety of surgical treatment of patients with chronic venous insufficiency

Authors

  • Рустем Рамзиевич Османов State institution «Zaycev V. T. Institute of general and urgent surgery of national academy of medical sciences of Ukraine» 1 Balakireva entry, Kharkiv, Ukraine, 61103, Ukraine https://orcid.org/0000-0001-8710-4109
  • Оксана Сергеевна Рябинская State institution «Zaycev V. T. Institute of general and urgent surgery of national academy of medical sciences of Ukraine» 1 Balakireva entry, Kharkiv, Ukraine, 61103, Ukraine
  • Борис Алексеевич Кабаков Kharkiv medical academy of postgraduate education 58 Amosova str., Kharkiv, Ukraine, 61176, Ukraine

DOI:

https://doi.org/10.15587/2313-8416.2016.67692

Keywords:

tumescent anesthesia, lidocaine, articaine, index of neutrophils lesion, allergy

Abstract

Background: For today there is no reliable method of determination of allergy to the local anesthetics in vitro.

Materials and methods: In this research authors evaluated the safety and efficiency of the choice of the solution for tumescent anesthesia. The choice depended on the result of “index of neutrophils lesion” that was evaluated in pre-surgical period. At 182 (83,5 %) interventions in 157 (83,1 %) patients with case anesthesia (CA) was used the Klein solution. In 36 (16,5 %) cases in 32 (16,9 %) patients for tumescence was used the original medicinal composition.

Results: the mean volume of administered anesthetic for the one patients at the one intervention is 366±92 ml (p<0,05) at the use of Klein solution and 540±167 ml (p<0,001) at the use of the offered medicinal composition. Allergic reactions were not revealed.

Conclusions: Evaluation of the “index of neutrophils lesion” in pre-surgical period allows orient in the choice of solution for tumescent anesthesia and, as the result, increases the safety of patient

Author Biographies

Рустем Рамзиевич Османов, State institution «Zaycev V. T. Institute of general and urgent surgery of national academy of medical sciences of Ukraine» 1 Balakireva entry, Kharkiv, Ukraine, 61103

Candidate of medical Science, Surgeon

Оксана Сергеевна Рябинская, State institution «Zaycev V. T. Institute of general and urgent surgery of national academy of medical sciences of Ukraine» 1 Balakireva entry, Kharkiv, Ukraine, 61103

Candidate of medical Science, Surgeon

Борис Алексеевич Кабаков, Kharkiv medical academy of postgraduate education 58 Amosova str., Kharkiv, Ukraine, 61176

Candidate of medical Science, Associate Professor

Department of anesthesiology, intensive care, transfusiology and haemotology

References

Drug Allergy: An Updated Practice Parameter (2010). Annals of Allergy, Asthma & Immunology, 105 (4), 259–273. doi: 10.1016/j.anai.2010.08.002

Mayorga, C., Celik, G., Rouzaire, P., Whitaker, P., Bonadonna, P., Cernadas, J. R. et. al. (2016). In vitro tests for Drug Hypersensitivity Reactions. An ENDA/EAACI Drug Allergy Interest Group Position Paper. Allergy. doi: 10.1111/all.12886

Pro orhanizatsiyni zakhody po vprovadzhennyu suchasnykh tekhnolohiy diahnostyky ta likuvannya alerhichnykh zakhvoryuvan' № 127/18 vid 02.04.2002 / MOZ Ukrayiny

Pro organizacijni zahody po vprovadzhennju suchasnyh tehnologij diagnostyky ta likuvannja alergichnyh zahvorjuvan' (2002). Nakaz Ministerstvo ohorony zdorov'ja ukrai'ny Akademija medychnyh nauk Ukrai'ny № 127/18.

Pro zatverdzhennja ta vprovadzhennja medyko-tehnologichnyh dokumentiv zi standartyzacii' medychnoi' dopomogy pry medykamentoznij alergii', vkljuchajuchy anafilaksiju (2015). Ministerstvo ohorony zdorov'ja Ukrai'ny № 916.

Boyce, J. A., Assa’ad, A., Burks, A. W., Jones, S. M., Sampson, H. A., Wood, R. A. et. al. (2010). Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report. Journal of Allergy and Clinical Immunology, 126 (6), 1105–1118. doi: 10.1016/j.jaci.2010.10.008

Gall, H., Kaufmann, R., Kalveram, C. (1996). Adverse reactions to local anesthetics: Analysis of 197 cases. Journal of Allergy and Clinical Immunology, 97 (4), 933–937. doi: 10.1016/s0091-6749(96)80067-4

Classification of lower extremity chronic venous disorders (2014). Available at: http://www.uptodate.com/contents/topic.do?topicKey=SURG/8177

Butterwick, K. J. (2016). Safety of Lidocaine During Tumescent Anesthesia for Liposuction. In Liposuction Principles and Practice. Springer. doi: 10.1007/3-540-28043-X_12

Boyko, V. V., Osmanov, R. R., Ryabins'ka, O. S., Kabakov, B. O. (2015). Pat. 100842 Ukrayina, MPK A61R23/02. Likars'ka kompozytsiya dlya tumestsentnoyi anesteziyi. Zayavnyk ta patentovlasnyk DU «Instytut zahal'noyi ta nevidkladnoyi khirurhiyi im. V.T.Zaytseva NAMNU». № u201502033; zayavl. 06.03.2015; opubl. 10.08.2015, Byul. № 15.

Published

2016-04-29

Issue

Section

Medical