Peculiarities of osteoarthritis in rats

Authors

DOI:

https://doi.org/10.15587/2313-8416.2016.69763

Keywords:

osteoarthritis, modeling, rats, CH3COOI acid, knee, cartilage

Abstract

Was received model of osteoarthritis in the rat line Wistar, by a one-time injection of CH3COOI acid into the knee joint. There changes in joint studied histological and clinical methods.On the 7-th day of the experiment was installed resemblance to similar changes in the joints of humans with acquired osteoarthritis

Author Biographies

Maria Drahulian, Institute of Molecular Biology and Genetics NAS of Ukraine 150 Ak. Zabolotnogo str., Kyiv, Ukraine, 03680

PhD, Researcher

Department of Cell Regulatory Mechanisms 

Tamara Gulko, Institute of Molecular Biology and Genetics, NAS of Ukraine 150 Ak. Zabolotnogo str., Kyiv, Ukraine, 03680

Junior Researcher

Department of Cell Regulatory Mechanisms 

Rostislav Bubnov, Clinical Hospital "Feofania" 21 Ak. Zabolotnogo str., Kyiv, Ukraine, 03680

Candidate of Medical Sciences

Ultrasound diagnosis

Polina Buchek, Institute of Molecular Biology and Genetics, NAS of Ukraine 150 Ak. Zabolotnogo str., Kyiv, Ukraine, 03680

PhD, Junior Researcher

Department of Cell Regulatory Mechanisms 

Dmitry Irodov, Institute of Molecular Biology and Genetics, NAS of Ukraine 150 Ak. Zabolotnogo str., Kyiv, Ukraine, 03680

Junior Researcher

Department of Cell Regulatory Mechanisms 

Ruslan German, Kharkiv regional Clinical Oncocenter 4 Lesoparkovskaya str., Kharkiv, Ukraine, 61070

Clinical oncologist

Mikhail Levkiv, Taras Shevchenko National University of Kyiv 60 Vladimirkaja str., Kyiv, Ukraine, 01033

Head of the vivarium

Svetlana Kostenko, National University of Life and Environmental Sciences of Ukraine 15 Geroiv Oborony str., Kyiv, Ukraine, 03041

Doctor of Biological Sciences, Professor

The Department of Genetics, Breeding and Biotechnology animals

References

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Published

2016-05-31

Issue

Section

Biological sciences