Deliberate hypotension for spine surgery in prone position

Authors

  • Микола Віталійович Лизогуб SI “Sytenko Institute of Spine and Joint Pathology AMS of Ukraine” Pushkinskaya street, 80, Kharkiv, Ukraine, 61024, Ukraine

DOI:

https://doi.org/10.15587/2313-8416.2015.38140

Keywords:

spinal surgery, deliberate hypotension, urapidil, general anesthesia, hemodynamics, prone position

Abstract

Background. Deliberate hypotension during spinal surgery aims to reduce intraoperative bleeding, thus providing better surgical visualization and less requirements for transfusion. A lot of methods of controlled hypotension are used nowadays. Each of them has advantages and disadvantages.

The aim of study was to examine safety and efficacy of hypotensive drug urapidil for providing deliberate hypotension for spinal surgery in prone position.

Material and methods. Eighty patients were elected and divided into 2 groups. Patients of the 1st group (n=43) received urapidil for controlled hypotension intraoperatively and patients of the 2nd group did not receive hypotensive drugs intraoperatively. Hemodynamics, time of surgery and restoration of consciousness after general anesthesia (Bidway test 20 min after anesthesia).

Results. Patients in urapidil group had reduction of blood pressure to desirable level without any critical drops of hemodynamics comparing to the patients of 2nd group (p<0,05) whose blood pressure did not change significantly during surgery. Controlled hypotension allowed to reduce the surgery time comparing to patients without hypotension (p<0,05). Awaking time (Bidway test) did not differ significantly between groups. No anesthesia complications were found during examination.

Conclusion. Deliberate hypotension with urapidil is safe and effective during spinal surgery in prone position as it allows to provide good surgical visualization without adverse effects

Author Biography

Микола Віталійович Лизогуб, SI “Sytenko Institute of Spine and Joint Pathology AMS of Ukraine” Pushkinskaya street, 80, Kharkiv, Ukraine, 61024

Candidate of Medical Sciences

Head of Department of Anaesthesiology and Intensive Therapy

References

Dongre, H. Sharma, V., Premendran, B., Dongre, A., Tidke, S. (2012). The efficacy of esmolol and nitroglycerine in creating dry operative field by producing controlled hypotension in spinal surgeries. IOSR Journal of Pharmacy, 2 (4), 26–33. doi: 10.9790/3013-24102633

Paul, J. E., Ling, E., Lalonde, C., Thabane, L. (2007). Deliberate hypotension in orthopedic surgery reduces blood loss and transfusion requirements: a meta-analysis of randomized controlled trials. Canadian Journal of Anesthesia, 54 (10), 799–810. doi: 10.1007/bf03021707

Lyzogub, M. V., Kostrikova, E. V., Khmyzov, A. O. (2013). Anesteziologichne zabezpechennja operatyvnych vtruchan u polozhenni na zhivoti [Anaesthesia in prone position]. Orthopaedics, Traumatology and Prosthetics, 3 (592), 99–106.

Postoperative Visual Loss Study Group (2012). Risk factors associated with ischemic optic neuropathy after spinal fusion surgery. Anesthesiology, 116 (1), 15–24.

Rodrigo, C. (1995). Induced hypotension during anesthesia with special reference to orthognatic surgery. Anesth Prog., 42 (2), 41–58.

Buch, J, Frederiksberg, C. (2010). Urapidil – antihypertensivnoye sredstvo s dvumja mechanismami deistvija: sovremennye aspecti klinicheskogo primenenija [Urapidil is antihypertensive drug with double action: modern aspects of clinical use]. Emergency Medicine, 5 (30), 5–14.

Dutton, R. (2004). Controlled hypotension for spinal surgery. European Spine Journal, 13 (S01), 66–71. doi: 10.1007/s00586-004-0756-7

Barrios, C., Pizá-Vallespir, G., Burgos, J., De Blas, G., Montes, E., Hevia, E., Collazos-Castro, J., Correa, C. (2014). Influence of hypotension and nerve root section on the ability to mobilize the spinal cord during spine surgery. An experimental study in a pig model. The Spine Journal, 14 (7), 1300-07. doi: 10.1016/j.spinee.2013.11.053

Published

2015-02-26

Issue

Section

Medical