Современная стратегия лечения гиперхолестеринемии
DOI :
https://doi.org/10.15587/2313-8416.2015.39266Mots-clés :
ишемическая болезнь сердца, семейная гиперхолестеринемия, статины, моноклональные антитела к пропротеин конвертазе субтилизин/кексин типа 9Résumé
В статье рассмотрены основные факторы сердечно-сосудистого риска, в частности гиперхолестеринемия, у больных ишемической болезнью сердца, приведена сравнительная характеристика эффективности статинов, описаны факторы, определяющие непереносимость и недостаточную эффективность стандартной гипохолестеринемической терапии. С точки зрения генетики рассмотрено перспективное направление научных исследований по разработке моноклональных антител к пропротеин конвертазе субтилизин/кексин типа 9, их влияние на показатели липидного профиля у пациентов высокого риска.
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(c) Tous droits réservés Игорь Владимирович Кузнецов 2015
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