Вплив хлорпірифосу на деякі фізіолого-біохімічні і функціональні характеристики гемоглобіну крові щурів
DOI :
https://doi.org/10.15587/2313-8416.2015.42536Mots-clés :
хлорпірифос, щурі, еритроцити, гемоглобін, каталаза, супероксиддисмутазаRésumé
Досліджено вплив хлорпірифосу на насичення гемоглобіну киснем, співвідношення його лігандних форм, активність каталази та супроксиддисмутази у гемолізатах еритроцитів периферичної крові щурів за умов введення щурам препарату хлорпірифосу впродовж однієї години. Зафіксовано зниження парціального тиску Оксигену, зростання вмісту метгемоглобіну та не лінійну залежність змін каталазної і супероксиддисмутазної активностей
Références
Salyha, Y. (2010). Biological effects assessment of chlorpyrifos and some aspects of its neurotoxicity.Visnyk of Lviv University. Biology series, 54, 3–14.
Vlizlo, V. V., Salyha, Y. T. (2012). Some problems of biological safety of aplication of pesticides in Ukraine. News of agrarian sciences, 1, 24–27.
Jin, Y., Liu, Z., Peng, T., Fu, Z. (2015). The toxicity of chlorpyrifos on the early life stage of zebrafish: A survey on the endpoints at development, locomotor behavior, oxidative stress and immunotoxicity. Fish & Shellfish Immunology, 43 (2), 405–414. doi: 10.1016/j.fsi.2015.01.010
Rosalovsky, V., Salyha, Y. (2013). New biochemical and physiological aspects of chlorpyrifos neurotoxicity. Toxicology Letters, 221, 200. doi: 10.1016/j.toxlet.2013.05.468
Whitney, K. D., Seidler, F. J., Slotkin, T. A. (1995). Developmental neurotoxicity of chlorpyrifos: cellular mechanisms.Toxicol Appl Pharmacol, 134 (1), 53–62. doi: 10.1016/j.toxlet.2013.05.468
Salyha, Y. T. (2013). Chlorpyrifos Leads to Oxidative Stress-Induced Death of Hippocampal Cells in Vitro. Neurophysiology, 45 (3), 193–199. doi: 10.1007/s11062-013-9356-7
Salyha, N. O. (2013). Activity of the glutathione system of antioxidant defense in rats under the action of L-glutamic acid Ukr. Biochem J., 85 (4), 40–47.
Salyha, Y. T. (2013). Antioxidant system indices in brain of rats intoxicated by chlorpyrifos. Studia Biologica, 7 (3), 85–96
Dudok, K. P., Vlokh, I. J., Vlokh, R. O. (2010). Structural and functional state of the erythrocytes, ligand forms of haemoglobin and content of molecules of middle mass in blood plasma of patients with schizophrenia disorders Studia Biologica, 4 (1), 15–26.
Dotsenko, O. I., Dotsenko, V. А., Mishchenko,A. M. (2010). The activity of erythrocytes superoxide dismutase and catalase and some other tissues at condition of low frequency vibration. Fhysics of Alive, 18 (1), 107–113.
Salyha, Yu. T., Tolokha, N. I., Stefanyshyn, O. M. (2011). Some parameters of antioxidant system in erythrocytes of rats under the chronic influence of chlorpyrifos. Medical i Clinical Chemistry, 13 (4), 103–106.
Lukaszewicz-Hussain, А. (2001). Organophosphate insecticide chlorfenvinphos affects superoxide dismutase, catalase and malondialdehyde in rat liver. Pol. J. of Environm, 10 (4), 279–282.
Ivanov, Y. T. (1975). Modification of spectrophotometric method for determining the curves of oxygen-hemoglobin dissociation. Bull.of experiment. Biology and medicine, 79 (11), 122–128.
Bilyy, O. I., Dudok, K. P., Lukyanets, V. (1998). Determination of hemoglobin and its ligand forms in whole blood by absorption spectroscopy. Lviv, 12.
Vlizlo, V. V., Fedoruk, R. S., Ratycz, I. B. et al. (2012). Laboratory methods of research in biology, stockbreeding and veterinary medicine. Lviv, SPOLOM, 761.
Vlizlo, V. V., Fedoruk, R. S., Makar, I. A. et al. (2004). Physiological and biochemical methods of research in biology, stockbreeding and veterinary medicine. Lviv, 399.
Lowry, O. H. (1951). Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193 (1), 265–275.
Salyha, Y. T., Rosalovsky, V. P. (2012). To the study of some parameters of antioxidant defense system and lipid peroxidation in blood of rats under the toxic influence of chlorpyrifos. Ukr morph. alm., 10 (3), 94–95.
Salyha, N., Salyha, Yu. (2013). Effect of L-glutamic acid on the activity of glutathione metabolism enzymes and intencity of peroxidation processes in rats Visn. Lviv Univ. Biol. Ser. 62, 61–67.
Salyha, Yu., Rosalovsky, V., Fedyakov, R. (2012). Glutathione system in erythrocytes of rats intoxicated by chlorpyrifos. Visn. Lviv Univ. Biol. Ser., 60, 99–104.
Téléchargements
Publié-e
Numéro
Rubrique
Licence
(c) Tous droits réservés Володимир Петрович Росаловський 2015
Cette œuvre est sous licence Creative Commons Attribution 4.0 International.
Our journal abides by the Creative Commons CC BY copyright rights and permissions for open access journals.
Authors, who are published in this journal, agree to the following conditions:
1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the journal under the terms of a Creative Commons CC BY, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this journal.
2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form in which it has been published by the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.
