Динаміка рівнів імунозапальних маркерів на тлі терапії кверцетином у хворих на ішемічну хворобу серця, асоційовану з гіпотиреозом
DOI :
https://doi.org/10.15587/2313-8416.2016.59038Mots-clés :
імунозапальні маркери, ішемічна хвороба серця, гіпотиреоз, кверцетинRésumé
Досліджено динаміку рівнів імунозапальних маркерів у хворих на ішемічну хворобу серця, асоційовану з гіпотиреозом, на тлі терапії кверцетином. Встановлено, що кверцетин у комплексному лікуванні хворих на ішемічну хворобу серця з супутнім гіпотиреозом впродовж 3 місяців поліпшує функціональний стан ендотелію та знижує активацію системного запального процесу
Références
Mitchenko, O., Lohvynenko, A., Romanov, V. (2010). Optymizatsiya likuvannya dyslipidemiy ta porushen' vuhlevodnoho obminiv u khvorykh z metabolichnym syndromom ta dysfunktsiyeyu shchytopodibnoyi zalozy [Optimization of treatment of dyslipidemia and disorders of carbohydrate metabolism in patients with metabolic syndrome and thyroid dysfunction]. Ukrainian Journal of Cardiology, 1, 73–80.
Tseng, F.-Y., Lin, W.-Y., Lin, C.-C., Lee, L.-T., Li, T.-C., Sung, P.-K., Huang, K.-C. (2012). Subclinical Hypothyroidism Is Associated With Increased Risk for All-Cause and Cardiovascular Mortality in Adults. Journal of the American College of Cardiology, 60 (8), 730–737. doi: 10.1016/j.jacc.2012.03.047
D’Alessandris, C., Lauro, R., Presta, I., Sesti, G. (2007). C-reactive protein induces phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 in L6 myocytes, thereby impairing the insulin signalling pathway that promotes glucose transport. Diabetologia, 50 (4), 840–849. doi: 10.1007/s00125-006-0522-y
Dal Lin, C., Tona, F., Osto, E. (2015). Coronary Microvascular Function and Beyond: The Crosstalk between Hormones, Cytokines, and Neurotransmitters. International Journal of Endocrinology, 2015, 1–17. doi: 10.1155/2015/312848
Kostoglou-Athanassiou, I., Ntalles, K. (2010). Hypothyroidism – new aspects of an old disease. Hippokratia, 14 (2), 82–87.
Ayers, S., Webb, P. (2014). Thyroid hormone analogues: their role in treatment of hyperlipidemia. Journal of Endocrinology, Diabetes & Obesity, 2 (3), 1042. Available at: http://www.jscimedcentral.com/Endocrinology/endocrinology-spid-role-thyroid-hormone-metabolic-homeostasis-1042.pdf
Kravchun, P., Lapshina, L., Zolotaykina, V. (2012). Dinamika urovney leykotriena S4, faktorov nespetsificheskogo vospaleniya, markerov oksidativnogo stressa, kardiogemodinamiki pri vklyuchenii vodorastvorimoy formyi kvertsetina v terapiyu ostroy serdechnoy nedostatochnosti [Dynamics of C4 leukotriene, factors of nonspecific inflammation, oxidative stress markers, cardiac hemodynamics when the water-soluble form of quercetin in the treatment of acute heart failure]. Scientific statements Belgorod State University. A series of "Medicine. Pharmacy", 4, 100–110.
Netjazhenko, V. Z., Mal'chevskaja, T. I., Mishanich, G. I. et al. (2010). Vybor metabolicheskoj terapii pri lechenii bol'nyh s ishemicheskoj bolezn'ju serdca. Novosti mediciny i farmacii, 7 (320), 8.
Schor, J. (2010). The influence of quercetin on exercise performance and muscle mitochondria. Natural Medicine Journal, 2 (5). Available at: http://www.naturalmedicinejournal.com/journal/2010-05/influence-quercetin-exercise-performance-and-muscle-mitochondria
Zaafan, M. A., Zaki, H. F., El-Brairy, A. I., Kenawy, S. A. (2013). Protective effects of atorvastatin and quercetin on isoprenaline-induced myocardial infarction in rats. Bulletin of Faculty of Pharmacy, Cairo University, 51 (1), 35–41. doi: 10.1016/j.bfopcu.2013.03.001
Kumar, S., Pandey, A. K. (2013). Chemistry and Biological Activities of Flavonoids: An Overview. The Scientific World Journal, 2013, 1–16. doi: 10.1155/2013/162750
Jeong, S.-M., Kang, M.-J., Choi, H.-N., Kim, J.-H., Kim, J.-I. (2012). Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice. Nutrition Research and Practice, 6 (3), 201. doi: 10.4162/nrp.2012.6.3.201
Perez-Vizcaino, F., Duarte, J. (2010). Flavonols and cardiovascular disease. Molecular Aspects of Medicine, 31 (6), 478–494. doi: 10.1016/j.mam.2010.09.002
Gunduz, M., Gunduz, E., Kircelli, F., Okur, N., Ozkaya, M. (2012). Role of Surrogate Markers of Atherosclerosis in Clinical and Subclinical Thyroidism. International Journal of Endocrinology, 2012, 1–6. doi: 10.1155/2012/109797
Lee, J. H., Shin, Y.-J., Oh, J.-H., Lee, Y.-J. (2012). Pharmacokinetic interactions of clopidogrel with quercetin, telmisartan, and cyclosporine A in rats and dogs. Archives of Pharmacal Research, 35 (10), 1831–1837. doi: 10.1007/s12272-012-1017-7
Pavlyukovych, N., Trefanenko, I., Pavlyukovych, O. (2013). Bilkovyy ta lipidnyy spektr krovi pry poyednanomu perebihu ishemichnoyi khvoroby sertsya ta khronichnoho nekal'kul'oznoho kholetsystytu: terapevtychni mozhlyvosti kvertsetynu [Protein and lipid spectrum of the blood flow combined with coronary heart disease and chronic non-calculous cholecystitis: therapeutic possibilities quercetin]. Medical Journal of Bukovina, 17 (3), 172–176.
Gergerlioglu, H., Demir, E., Alp, M., Oz, M. (2015). Effects of quercetin in IL-6 and TNF-α levels in diabetic rats. The FASEB Journal, 29 (1).
Mahmoud, M. F., Hassan, N. A., El Bassossy, H. M., Fahmy, A. (2013). Quercetin Protects against Diabetes-Induced Exaggerated Vasoconstriction in Rats: Effect on Low Grade Inflammation. PLoS ONE, 8 (5), e63784. doi: 10.1371/journal.pone.0063784
Wang, L., Chen, J., Wang, B., Wu, D., Li, H., Lu, H. et. al (2014). Protective effect of quercetin on lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammatory cell influx. Experimental Biology and Medicine, 239 (12), 1653–1662. doi: 10.1177/1535370214537743
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