Эпителиально-мезенхимальная трансормация папиллярных микрокарцином щитовидной железы
DOI:
https://doi.org/10.15587/2313-8416.2015.39327Słowa kluczowe:
папиллярные микрокарциномы щитовидной железы, эпителиально-мезенхимальная трансформация, метастазы в лимфатические узлыAbstrakt
В 28 случаях папиллярных микрокарцином щитовидной железы выявлено повышение экспрессии виментина в зонах инвазии (р<0,01) и метастазах (<0,001). Для микрокарцином с выраженной экспрессией виментина трабекулярно-солидного строения характерно повышение уровня экспрессии ММР-9 (р<0,005), VEGF (р<0,05), снижение уровня экспрессии NIS (р<0,005), метастазирование в регионарные лимфатические узлы (р<0,001).
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Copyright (c) 2015 Ирина Ивановна Яковцова, Игорь Владимирович Ивахно, Оксана Владимировна Долгая, Анрей Евгениевич Олейник, Светлана Владимировна Данилюк
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