Патогенетичні аспекти циркуляційно-гідратаційного та кислотно-основного станів в перебігу токсичного епідермального некролізу
DOI:
https://doi.org/10.15587/2313-8416.2015.57330Słowa kluczowe:
медикаменти, синдром Лайєлла, гомеостаз, гемоциркуляція, ацидоз, дерматоз, метаболізмAbstrakt
Обстежено 13 хворих токсичним епідермальним некролізом (ТЕН) медикаментозного ґенезу, встановлено значні циркуляторно-гідратаційні розлади (низький артеріальний систолічний і пульсовий тиск, вкрай низький ЦВТ, шоковий індекс 2-3 ступеню) та порушення кислотно-основного стану (метаболічний ацидоз, субкомпенсований дихальним алкалозом, зсув буферних основ), що потребують адекватної волемічної корекції, з урахуванням визначених патогенетичних ланок даного дерматозу
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