https://journals.uran.ua/sr_bio/issue/feed ScienceRise: Biological Science 2025-01-14T12:02:59+02:00 Yuliia Nikolaieva bio@entc.com.ua Open Journal Systems <p>«ScienceRise: Biological Science» – scientific peer-reviewed journal, published 4 times a year, included in category “B” «List of scientific professional editions of Ukraine» for specialty 091-Biology (Сertificated by order of Ministry of Education and Science of Ukraine No. 612 from 07.05.2019) and for specialty 211- Veterinary medicine (Сertificated by order of Ministry of Education and Science of Ukraine No. 320 from 07.04.2022).</p> <p style="font-weight: 400;">The goal of "ScienceRise: Biological Science" journal is to provide a platform for scientists to share scientific data in all aspects of the life sciences.</p> <p style="font-weight: 400;">The concept of "Ecosystems", which is considered from three points of view, is at the center of the researched issues of the journal:</p> <p style="font-weight: 400;">– biota, which is affected by external factors caused by human activity,<br />– the influence of environmental factors on the health of people and animals,<br />– medicinal properties of plants for their use in medicinal preparations.</p> <p style="font-weight: 400;">Such a focus of research should cover applied aspects related to human and animal health: identification of the causes of diseases and diagnosis based on microbiological studies, prevention, effects of medicinal drugs and supplements, biotechnological solutions for improving the state of health care and the environment.</p> <p style="font-weight: 400;">Therefore, the areas of scientific research covered in the "ScienceRise: Biological Science" journal are divided as follows:</p> <p style="font-weight: 400;">Life Sciences:</p> <ul> <li style="font-weight: 400;">Biological and agricultural sciences (plants that have medicinal properties);</li> <li style="font-weight: 400;">Biochemistry, genetics and molecular biology (biochemistry, biotechnology);</li> <li style="font-weight: 400;">Environmental science (ecology, health, toxicology and mutagenesis);</li> <li style="font-weight: 400;">Immunology and microbiology (applied microbiology and biotechnology, immunology, parasitology, virology).</li> </ul> <p style="font-weight: 400;">Health Sciences</p> <ul> <li style="font-weight: 400;">Pharmacology, toxicology and pharmaceuticals;</li> <li style="font-weight: 400;">Veterinary and veterinary medicine.</li> </ul> <p><a href="https://portal.issn.org/resource/ISSN/2519-8017">ISSN 2519-8017</a>, <a href="https://portal.issn.org/resource/ISSN/2519-8025ISSN">E-ISSN 2519-8025</a>, <a href="https://portal.issn.org/resource/ISSN/2519-8017">ISSN-L 2519-8017</a><br /><br />Drawing up the items of the publication ethics policy of the journal «ScienceRise: Biological Science» Editors followed the recommendations of Committee on Publication Ethics<a href="http://publicationethics.org/"> (COPE)</a>.</p> https://journals.uran.ua/sr_bio/article/view/320781 Botulotoxin as the most typical product of the biotechnology for aesthetic cosmetology and the study of subjective attitude towards its use among the Ukrainian population sample 2025-01-14T00:31:47+02:00 Olga Filiptsova philiptsova@yahoo.com Olga Naboka olganaboka2012@gmail.com Natalia Khokhlenkova hohnatal@gmail.com Kateryna Kalashnik katerinakalashnik21@gmail.com Olha Kaliuzhnaia kalyuzhnayao.s@gmail.com Nataliia Dvinskykh begunova1203@gmail.com Alina Soloviova soloviova.alina@gmail.com Andriy Zakhariev vagabond19973@gmail.com Liudmyla Petrovska l.s.petrovskaya96@gmail.com <p><strong>The aim </strong>of the study was to analyze the effectiveness of botulinum therapy in aesthetic cosmetology and to consider the influence of various factors on the decision to perform the procedure.</p> <p><strong>Materials and methods.</strong> The work used content analysis of literary sources, analytical method, and online survey of females and males of different generations regarding the botulinum therapy procedure.</p> <p><strong>Results and discussion.</strong> Botulinum toxin was historically first used to smooth glabellar wrinkles, and then its use was expanded to other areas of the face. There are seven types of botulinum toxin (A, B, C, D, E, F, and G). Experience with the use of botulinum therapy for aesthetic purposes shows that clinical ineffectiveness is extremely rare. Depending on gender, the reaction to procedures with the introduction of botulinum toxin for cosmetic purposes is different. Females are more aware of the botulinum therapy procedure than males. Botulinum toxin therapy is most common among younger adults (25 to 39 years old).</p> <p><strong>Conclusions.</strong> Interest in botulinum toxin therapy increases with age. People, interested in botulinum toxin therapy, are more likely to visit a cosmetologist regularly. Profession affects person’s involvement in the botulinum toxin therapy procedure. The largest proportion of the respondents who have undergone botulinum toxin therapy is observed among the medical and beauty sectors, business and management. The largest number of the respondents who want to try botulinum toxin therapy is among students. This may indicate the openness of the younger generation to experiments and understanding the importance of continuing their youth in the future for as long as possible. The study showed that BMI does not affect respondents’ involvement in the botulinum toxin therapy procedure. The Internet is the main source of information about botulinum toxin therapy for a significant number of the respondents, regardless of their involvement in this procedure. The participants prioritize the result of botulinum toxin therapy, not its cost</p> 2024-09-30T00:00:00+03:00 Copyright (c) 2025 Ольга Володимирівна Філіпцова, Ольга Іванівна Набока, Наталя Вікторівна Хохленкова, Катерина Юріївна Калашнік, Ольга Сергіївна Калюжная, Наталія Власівна Двінських, Аліна Володимирівна Соловйова, Андрій Вікторович Захар’єв, Людмила Станіславівна Петровська https://journals.uran.ua/sr_bio/article/view/320788 Effectiveness of a new combined remedy based on a derivative of dicarbonic acid in conditions of drug-induced hepatitis 2025-01-14T12:02:59+02:00 Anastasia Morozyuk essirejn@gmail.com Maria Kudrya lab-tox@ukr.net Natalya Melnykivska lab-tox@ukr.net Nonna Ustenko lab-tox@ukr.net Yulia Laryanovska yulasechka38@gmail.com <p><strong>The aim of the </strong>study is to evaluate the effect of a new combined remedy based on dicarboxylic acid and a selenium-containing compound on the functional and metabolic state of the liver in conditions of prolonged paracetamol-induced hepatitis.</p> <p><strong>Materials and methods </strong>The study was conducted on outbred white rats weighing 200-250 g in compliance with all principles of ethical treatment of animals. Drug-induced liver injury was modeled by oral administration of paracetamol per os for four weeks at a dose of 600 mg per kg body weight. Animals were divided into groups: I - control, which was injected with a solvent (2 % starch solution); II - rats with paracetamol-induced hepatitis; III - rats with hepatitis, which received a new agent based on a dicarboxylic acid derivative and a selenium-containing compound at a dose of 32 mg/kg b.w. Verification of functional and metabolic disorders of the liver was carried out using biochemical methods and histological examination of the liver tissue.</p> <p><strong>Results</strong> Significant changes in the activity of hepatic enzymes in animals from the induced hepatitis group compared to intact control animals, increased levels of sialic acids in the blood serum and liver, etc. were recorded. Structural changes in the liver tissue of animals with induced hepatitis were also observed compared to intact control animals. The use of the new remedy led to the normalization of the indicators.</p> <p><strong>Conclusions</strong>. In the conditions of paracetamol-induced hepatitis, changes in biochemical parameters in the blood serum and liver homogenate were observed, indicating the development of autoimmune processes in the body. Correction with the new remedy led to the restoration of liver enzyme activity and a decrease in the content of sialic acids in the blood serum and liver homogenate of experimental animals. The new combined remedy based on a dicarboxylic acid derivative and a selenium-containing compound is effective and promising as a potential drug for the correction of liver disorders in the setting of drug-induced hepatitis</p> 2024-09-30T00:00:00+03:00 Copyright (c) 2025 Анастасія Юріївна Морозюк, Марія Яківна Кудря, Наталя Викторівна Мельниківська, Нонна Василівна Устенко, Юлія Борисівна Лар’яновська