https://journals.uran.ua/sr_pharm/issue/feed 2026-01-27T11:59:24+02:00 Yuliia Nikolaieva pharm@entc.com.ua Open Journal Systems <p><em>«ScienceRise: Pharmaceutical Science» </em><em>–</em> scientific peer-reviewed journal, published 6 times a year, included in category «A» «List of scientific professional editions of Ukraine» (Сertificated by order of Ministry of Education and Science of Ukraine No. 420 from 19.04.2021).</p> <p>Registration of an entity in the media sector: Decision of the National Council of Ukraine on Television and Radio Broadcasting No. 695 dated August 10, 2023, protocol No. 17 (media identifier R30-01130).</p> <p><em>The main mission of the journal </em>– dissemination of the results of scientific research aimed at ensuring the quality of pharmaceutical assistance to the population through targeted search and modern pharmaceutical development of innovative medicines, the creation of modern quality management systems at pharmaceutical enterprises in the industry.</p> <p>In the journal<em> «ScienceRise: Pharmaceutical Science» </em>publishes research designed and implemented taking into account the Quality by design concept with widespread use of computational methods.</p> <p>The journal is intended for scientists, pharmacists, doctors, educators, and healthcare professionals.</p> <p><em>Innovations in pharmaceutical science - </em>for practical use.</p> <p><a href="https://portal.issn.org/resource/ISSN/2519-4844ISSN" target="_blank" rel="noopener noreferrer">ISSN 2519-4844</a>, <a href="https://portal.issn.org/resource/ISSN/2519-4852" target="_blank" rel="noopener noreferrer">E-ISSN 2519-4852</a>, <a href="https://portal.issn.org/resource/ISSN/2519-4844ISSN">ISSN-L 2519-4844</a><br /><br />Drawing up the items of the publication ethics policy of the journal «ScienceRise: Pharmaceutical Science» Editors followed the recommendations of Committee on Publication Ethics <a href="http://publicationethics.org/">(COPE)</a>.</p> https://journals.uran.ua/sr_pharm/article/view/349856 2026-01-15T14:07:09+02:00 Kateryna Uminska uminska.kateryna@pharm.zt.ua Liudas Ivanauskas Liudas.Ivanauskas@lsmu.lt Laurynas Jarukas laurynas.jarukas@lsmuni.lt Victoriya Georgiyants vgeor@nuph.edu.ua Olha Mykhailenko o.mykhailenko@nuph.edu.ua

<p>Epilobium hirsutum L. is widely used in traditional European medicine to treat urological and inflammatory conditions. Despite its widespread use, no pharmacopoeial monographs on its plant material have been published to date. The <strong>aim</strong> of this study was to establish physicochemical parameters and identify marker phenolic compounds for the standardisation of plant leaves.</p> <p><strong>Method</strong>. Seven E. hirsutum leaf samples collected in Ukraine, Lithuania, and Poland for analysis. The following parameters were analysed: loss on drying, total ash, and acid-insoluble ash content according to the State Pharmacopoeia of Ukraine. The qualitative composition was analysed using high-performance thin-layer chromatography (HPTLC), and the quantitative analysis of total phenolic compounds, flavonoids, and specific marker compounds was performed using UV spectrophotometry and HPLC-DAD.</p> <p><strong>Results</strong>. As a result, it was established that the content of foreign impurities did not exceed 2% in the analysed samples, the drying loss was 6.4–8.1%, and the total ash was 4.0–5.7%. The HPTLC method was used to determine gallic acid, isoquercitrin, avicularin, guijaverin and hyperoside as key compounds for the plant quality control. Total phenolics ranged between 0.78 and 1.52 mg GAE/g dw, while total flavonoid content was 1.9–5.5 mg HE/g dw. The HPLC method showed that the dominant polyphenolics is oenothein B (39.9–65.7 mg/g), followed by oenothein A, gallic, chlorogenic, and ellagic acids, hyperoside, isoquercitrin, and quercetin. The present components can be proposed for the development of raw material standardisation parameters.</p> <p><strong>Conclusion</strong>. The obtained data confirm that E. hirsutum leaves meet requirements of the State Pharmacopeia of Ukraine and European Pharmacopoeia and can serve as the basis for developing a monograph. Oenothein B, hyperoside, and gallic acid can be proposed as identification markers; in addition, the total phenolic content can be assessed</p>

2026-01-19T00:00:00+02:00 Copyright (c) 2026 Kateryna Uminska, Liudas Ivanauskas, Laurynas Jarukas, Victoriya Georgiyants, Olha Mykhailenko