The dynamics of markers of a shock state in traumatic blood loss depending on fluid resuscitation type.

Authors

  • D. A. Krishtafor
  • O. M. Klygunenko

DOI:

https://doi.org/10.26641/2307-0404.2017.4.117672

Keywords:

multiple trauma, bleeding, bleeding management, multiple organ failure, liberal fluid resuscitation, restrictive fluid resuscitation

Abstract

The aim of the study was to determine the effect of quantitative and qualitative changes in fluid resuscitation on the dynamics of markers of the shock state in patients with multiple trauma. 73 patients with multiple trauma were divided into two groups, depending on the fluid resuscitation type (liberal or restrictive). The parameters of hemodynamics, hourly diuresis, general blood test, coagulogram, acid-base and gas composition of blood were studied. A decrease in the infusion volume in traumatic blood loss due to the restriction of the crystalloids and colloids volume allowed to effectively reduce such manifestations of shock as hypotension, tachycardia and acidosis, to provide an adequate rate of diuresis. In restrictive infusion group the duration of vasopressor support was shorter, the fluctuations in peripheral blood parameters were less pronounced, coagulation normalized earlier, positive water balance was significantly lower, mortality and the number of complications were reduced. Restriction of fluid resuscitation volume allows to successfully treat shock and decrease multiple organ dysfunction, number of complications and mortality.

Author Biographies

D. A. Krishtafor

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of Anesthesiology, Intensive Therapy and Medicine of emergency conditions
of Postgraduate Education Faculty
V. Vernadsky str., 9, Dnipro, 49044, Ukraine

O. M. Klygunenko

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of Anesthesiology, Intensive Therapy and Medicine of emergency conditions
of Postgraduate Education Faculty
V. Vernadsky str., 9, Dnipro, 49044, Ukraine

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Published

2017-12-06

How to Cite

1.
Krishtafor DA, Klygunenko OM. The dynamics of markers of a shock state in traumatic blood loss depending on fluid resuscitation type. Med. perspekt. [Internet]. 2017Dec.6 [cited 2024Apr.25];22(4):68-73. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/117672

Issue

Section

CLINICAL MEDICINE