Evaluation of life quality of patients with chronic hepatitis C.

Authors

  • O. P. Schevchenko-Makarenko
  • L. R. Schostakovych-Korets`ka
  • Z. O. Chykarenko
  • V. D. Tkachenko
  • O. O. Lisnicha

DOI:

https://doi.org/10.26641/2307-0404.2017.4.117677

Keywords:

quality of life, chronic viral hepatitis C, co-infection HIV / HCV questionnaire, CLDQ

Abstract

The article presents the adap­tation data of the quality of life questionnaire (QOL) in patients with chronic viral hepatitis C (CVHC). Ball score of QOL of patients with CVHC was 5.09±1.04, 2nd group (with co-infection with HIV / HCV) - 4.60±1.13, control group - 5.92±0.52 (p<0.05)). The results of the analysis show that co-infection HIV / HCV is a serious problem for patients and significantly affects QOL. The use of the QOL questionnaire for chronic liver disease is a sensitive tool for measuring QOL in patients with CVHC and co-infection HIV / HCV. This informative and economical method can be implemented to assess the patient's health both at the group and individual levels in patients with chronic liver disease in the population ofUkraine.

Author Biographies

O. P. Schevchenko-Makarenko

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine» *
Department of Infectious Diseases
V. Vernadsky str., 9, Dnipro, 49044, Ukraine

L. R. Schostakovych-Korets`ka

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine» *
Department of Infectious Diseases
V. Vernadsky str., 9, Dnipro, 49044, Ukraine

Z. O. Chykarenko

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine» *
Department of Infectious Diseases
V. Vernadsky str., 9, Dnipro, 49044, Ukraine

V. D. Tkachenko

CE «Dnipropetrovsk City Clinical Hospital N 21 named after prof. E.G. Popkova» DRC» **
Kanatnaya str., 17, Dnipro, 49006, Ukraine

O. O. Lisnicha

CE «Dnipropetrovsk City Clinical Hospital N 21 named after prof. E.G. Popkova» DRC» **
Kanatnaya str., 17, Dnipro, 49006, Ukraine

References

Vakalyuk IP, Drapchak IM. [Features of the cour­se of a permanent form of atrial fibrillation in patients with concomitant chronic diffuse inflammatory diseases of the liver on the background of prolonged warfarin therapy]. Halytskyy likarskyy visnyk. 2015;22(1):13-17. Ukrainian.

Khalafyan AA. [Statistica 6. Statistical analysis: a manual for the higher educational institutions]. Moskva, Binom-Press. 2010;528. Russian.

Lekhan VM, Ipatov AV, Huk AP, Zyukov OL. [Quality of life in medical research]. Visnyk sotsialnoyi hihiyeny ta orhanizatsiyi okhorony zdoroviya Ukrayiny. 2004;1:57-61. Ukrainian.

Shevchenko-Makarenko ОP, Shostakovych-Ko­retskaya LR, Semiletova VV, et al. [Quality of life in HIV-infected patients with different comorbid patho­logical conditions]. Preventive medicine. 2016;3-4(27):168-9. Ukrainian.

Matsushita H, Ikeda F, Iwasaki Y, et al. Asses­sment of health-related quality of life and how it predicts the out­come of pegylated interferon and ribavirin therapy for chro­nic hepatitis C. J Gastroenterol Hepatol. 2014;29:337-43.

Younossi ZM, Guyatt G, Kiwi M, et al. Deve­lopment of a disease specific questionnaire to measure health related quality of life in patients with chronic liver disease. Gut. 1999;45:295-300.

Kallman J, O’Neil MM, Larive B, et al. Fatigue and health-related quality of life (HRQL) in chronic hepatitis C virus infection. Dig Dis Sci. 2007;52:2531–9.

Hollander A, Foster GR, Weiland O. Health-re­lated quality of life before, during and after combination therapy with interferon and ribavirin in unselected Swedish patients with chronic hepatitis C. Scand J Gas­troenterol. 2006;41:577-85.

Shevchenko-Makarenko О, Shostakovych-Ko­ret­skaya L, Timofeeva L. Quality of life in patients with HCV/ HIV co-infection. Reviews in Antiviral Therapy & Infectious diseases, 2016;9:9.

Schulz KH, Kroencke S, Ewers H, et al. The factorial structure of the Chronic Liver Disease Ques­tionnaire (CLDQ). Qual Life Res. 2008;17:575-84.

Popovic DDJ,KovacevicNV, Kisic Tepavcevic DB et al. Validation of the chronic liver disease ques­tionnaire in Serbian patients. World J Gastroenterol. 2013;19:4950-57.

Wells GA, Russell AS, Haraoui B, et al. Validity of quality of life measurement tools - from generic to disease-specific. J Rheumatol Suppl. 2011;88:2-6.

Ware JE. Interpreting SF–36 summary health measures: a response. Quality of life research, 2001;10(5):405-13.

Younossi ZM, Boparai N, McCormick M. A di­sease-specific health-related quality of life instrument for chronic hepatitis C: CLDQ-HCV. Hepatology. 2000;32:838.

Younossi ZM, Stepanova M, Henry L. Perfo­rmance and Validation of Chronic Liver Disease Ques­tionnaire-Hepatitis C Version (CLDQ-HCV) in Clinical Trials of Patients with Chronic Hepatitis C. Value Heals. 2016;19(5):544-51. doi: 10.1016/j.jval.2016.02.005. Epub 2016 Apr 26.

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Published

2017-12-06

How to Cite

1.
Schevchenko-Makarenko OP, Schostakovych-Korets`ka LR, Chykarenko ZO, Tkachenko VD, Lisnicha OO. Evaluation of life quality of patients with chronic hepatitis C. Med. perspekt. [Internet]. 2017Dec.6 [cited 2024Nov.29];22(4):81-6. Available from: https://journals.uran.ua/index.php/2307-0404/article/view/117677

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Section

CLINICAL MEDICINE