The phenotypes of chronic heart failure in patients with ischemic heart disease combined with chronic obstructive pulmonary disease.
Keywords:heart failure, phenotypes, ischaemic heart disease, chronic obstuctive pulmonary disease
The aim of this study: on the basis of clinical and instrumental complex investigation of 320 patients with chronic heart failure (CHF) of ischemic etiology combined with chronic obstructive pulmonary disease (COPD) it was proposed to identify several phenotypes of including CHF with preserved ejection fraction (CHFpEF) without right ventricular dysfunction (RVD); CHFpEF with RVD; CHFpEF with right-side failure (RSF); CHF with reduced EF (CHFrEF) plus RSF (biventricular). Identification of these phenotypes creates the pathophysiologic basis to development of rathional pharmacotherapy of CHF in patients with ischemic heart disease combined with COPD.
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